2. Consider two loci (locus 1 with alleles A and a, and locus 2 with alleles B and b) with allele frequencies p = 0.4 and s= 0.7. a) What are the expected gamete frequencies if the two loci are in linkage equilibrium? p=0.4 p(AB) = p(aB) = q= s = 0.7 p(Ab) = p(ab) = t =

Human Anatomy & Physiology (11th Edition)
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Author:Elaine N. Marieb, Katja N. Hoehn
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Chapter1: The Human Body: An Orientation
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BE
2
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2. Consider two loci (locus 1 with alleles A and a, and locus 2 with alleles B and b) with allele frequencies p = 0.4
and s= 0.7.
a) What are the expected gamete frequencies if the two loci are in linkage equilibrium?
p=0.4
p(AB) =
p(aB) =
:0
F2
English (United States) Accessibility: Unavailable
p(AB) =
p(aB) =
#3
80
b) What is the value Dmax assuming the case of maximum positive disequilibrium? Hint: it is the smaller value
between the two products of allele frequencies.
E
q=
c). Calculate the gametic frequencies assuming the case of maximum positive disequilibrium (Hint: remember
that D is used to measure the deviation from random association between alleles at the two loci 1 and 2, so that
for gamete AB for example, D = p(AB) - p*s).
D
$
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p(ab) =
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p(ab) =
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Transcribed Image Text:BE 2 W S E- 2. Consider two loci (locus 1 with alleles A and a, and locus 2 with alleles B and b) with allele frequencies p = 0.4 and s= 0.7. a) What are the expected gamete frequencies if the two loci are in linkage equilibrium? p=0.4 p(AB) = p(aB) = :0 F2 English (United States) Accessibility: Unavailable p(AB) = p(aB) = #3 80 b) What is the value Dmax assuming the case of maximum positive disequilibrium? Hint: it is the smaller value between the two products of allele frequencies. E q= c). Calculate the gametic frequencies assuming the case of maximum positive disequilibrium (Hint: remember that D is used to measure the deviation from random association between alleles at the two loci 1 and 2, so that for gamete AB for example, D = p(AB) - p*s). D $ 4 R F do 5 % F5 s = 0.7 T p(Ab) = p(ab) = G p(Ab) = p(ab) = MacBook Air () > 6 ss Fo C Y No Spacing & 7 H t= ← F7 U N * Heading 2 8 J DII FB ( 9 Focus E Fo K M ) O 0 L < L' P
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