Having studied the process by which DNA directs the synthesis of proteins, you should be ready to decode some D " messages. To do this, you must follow the procedure of protein synthesis as this is taking place right now in your ce cuts! Practice these steps by following and finishing the partially solved message below. 1: "Build" the mRNA molecule, matching the RNA nucleotides to the DNA nucleotides properly, letter by letter. (For purposes of simplicity, it will be assumed that this mRNA is bacterial; there are no introns to cut out!) 2: Figure out the tRNA triplets (codons) which would fit the mRNA triplets (letter by letter). 3: Look up each TRNA codon in the TRNA Dictionary (below), and find the corresponding symbol and amino acid eviation for that codon. Record that one-letter symbol (and its amino acid) below each codon. "Spc" = "space". If you ha this correctly, the symbols should spell out a meaningful message in English. Remember, C always pairs with G, G always pairs with C, A pairs with T (in DNA) or U (in RNA), T!pairs with A, a ENA) pairs with A (in DNA). Clues: C & G are curved letters; Ą & T are angular; U is used in RNA in place of T. When you finish the sample message below, decode the special message assigned to you (from the sheet with many sages). Be sure to show the details of your solution on the Practice Sheet provided, and hand it in. In your DNA exam, you be expected to do this from memory (provjded with the tRNA Dictionan

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SAY IT WITH DNA: PROTEIN SYNTHESIS WORKSHEET: Practice Pays
Having studied the process by which DNA directs the synthesis of proteins, you should be ready to decode some DNA
"secret" messages. To do this, you must follow the procedure of protein synthesis as this is taking place right now in your cells; no
short cuts! Practice these steps by following and finishing the partially solved message below.
STEP 1: "Build" the mRNA molecule, matching the RNA nucleotides to the DNA nucleotides properly, letter by letter.
(For purposes of simplicity, it will be assumed that this mRNA is bacterial; there are no introns to cut out!)
STEP 2: Figure out the tRNA triplets (codons) which would fit the mRNA triplets (letter by letter).
STEP 3: Look up each tRNA codon in the tRNA Dictionary (below), and find the corresponding symbol and amino acid
abbreviation for that codon. Record that one-letter symbol (and its amino acid) below each codon. "Spc" = "space". If you have
done this correctly, the symbols should spell out a meaningful message in English.
Remember, C always pairs with G, G always pairs with C, A pairs with T (in DNA) or U (in RNA), Tlpairs with A, and U
(in RNA) pairs with A (in DNA). Clues: C & G are curved letters; A & T are angular; U is used in RNA in place of T.
When you finish the sample message below, decode the special message assigned to you (from the sheet with many
messages). Be sure to show the details of your solution on the Practice Sheet provided, and hand it in. In your DNA exam, you
will be expected to do this from memory (provided with the tRNA Dictionary).
PARTIALLY SOLVED MESSAGE
GIVEN: DNA code message --> GAA TAG AAA CTT ACT TAG AGC ATT CCT GCC CTT CGA TGC ATC
SOLUTION (steps 1-4)
1. MRNA (built to match
the DNA message,
letter for letter-
-> CUU AUC UUU GAA UGA AỤC UCG
... .... ..
2. TRNA (determined by
matching letters (bases)
with those in mRNA)-
AAA
-> GAA UAG AAA CUU ACU UAG
3. Amino acids carried by
each tRNA (according to
dictionary, below)---
G
I
u
e
u
4. Symbols of amino acids:---->
F
E
DICTIONARY OF †RNA CODONS & THEIR AMINO ACIDS (SYMBOLS & ABBREVIATIONS)
tRNA| sym|
tRNA sym
AA
AA
tRNA sym
AA
tRNA sym
AA
AAA
F
Phe
CAA
CÁC
V
Val
GAA
Leu
UAA
Iso
AAC
L
Leu
Val
GAC
Leu
UAC
M
Met
AAG
F
Phe
CAG
Val
GAG
Leu
UAG
UAU
Iso
AAU
ACA
ACC
ACG
ACU
Leu
CAU
CCA
Val
GAU
Leu
Iso
Cys
Trp
Cys
Gly
Gly
Gly
Gly
Ala
GCA
Arg
Arg
Arg
Arg
Pro
UCA
UCC
R
UCG
S
Ser
W
CCC
CCG
CCU
CGA
CGC
CGG
CGU
CUA
CUC
CUG
G
GCC
GCG
R
Arg
Ser
R
spc
Ser
Ser
Ser
Ser
Туг
GCU
UCU
UGA
UGC
UGG
UGU
UUA
UUC
UUG
UUU
Arg
Thr
Thr
AGA
P.
P.
GGA
T.
AGC
Ala
GGC
AGG
AGU
AUA
AUC
Pro
Pro
Pro
His
S
Ala
Ala
Asp
Glu
Asp
Glu
GGG
Thr
GGU
GUA
GUC
GUG
GUU
P.
The
Y.
D
Asn
spc
AUG
AUU
Glu
His
Glu
Lys
Asn
Lys
Туг
H.
spc
CUU
Transcribed Image Text:SAY IT WITH DNA: PROTEIN SYNTHESIS WORKSHEET: Practice Pays Having studied the process by which DNA directs the synthesis of proteins, you should be ready to decode some DNA "secret" messages. To do this, you must follow the procedure of protein synthesis as this is taking place right now in your cells; no short cuts! Practice these steps by following and finishing the partially solved message below. STEP 1: "Build" the mRNA molecule, matching the RNA nucleotides to the DNA nucleotides properly, letter by letter. (For purposes of simplicity, it will be assumed that this mRNA is bacterial; there are no introns to cut out!) STEP 2: Figure out the tRNA triplets (codons) which would fit the mRNA triplets (letter by letter). STEP 3: Look up each tRNA codon in the tRNA Dictionary (below), and find the corresponding symbol and amino acid abbreviation for that codon. Record that one-letter symbol (and its amino acid) below each codon. "Spc" = "space". If you have done this correctly, the symbols should spell out a meaningful message in English. Remember, C always pairs with G, G always pairs with C, A pairs with T (in DNA) or U (in RNA), Tlpairs with A, and U (in RNA) pairs with A (in DNA). Clues: C & G are curved letters; A & T are angular; U is used in RNA in place of T. When you finish the sample message below, decode the special message assigned to you (from the sheet with many messages). Be sure to show the details of your solution on the Practice Sheet provided, and hand it in. In your DNA exam, you will be expected to do this from memory (provided with the tRNA Dictionary). PARTIALLY SOLVED MESSAGE GIVEN: DNA code message --> GAA TAG AAA CTT ACT TAG AGC ATT CCT GCC CTT CGA TGC ATC SOLUTION (steps 1-4) 1. MRNA (built to match the DNA message, letter for letter- -> CUU AUC UUU GAA UGA AỤC UCG ... .... .. 2. TRNA (determined by matching letters (bases) with those in mRNA)- AAA -> GAA UAG AAA CUU ACU UAG 3. Amino acids carried by each tRNA (according to dictionary, below)--- G I u e u 4. Symbols of amino acids:----> F E DICTIONARY OF †RNA CODONS & THEIR AMINO ACIDS (SYMBOLS & ABBREVIATIONS) tRNA| sym| tRNA sym AA AA tRNA sym AA tRNA sym AA AAA F Phe CAA CÁC V Val GAA Leu UAA Iso AAC L Leu Val GAC Leu UAC M Met AAG F Phe CAG Val GAG Leu UAG UAU Iso AAU ACA ACC ACG ACU Leu CAU CCA Val GAU Leu Iso Cys Trp Cys Gly Gly Gly Gly Ala GCA Arg Arg Arg Arg Pro UCA UCC R UCG S Ser W CCC CCG CCU CGA CGC CGG CGU CUA CUC CUG G GCC GCG R Arg Ser R spc Ser Ser Ser Ser Туг GCU UCU UGA UGC UGG UGU UUA UUC UUG UUU Arg Thr Thr AGA P. P. GGA T. AGC Ala GGC AGG AGU AUA AUC Pro Pro Pro His S Ala Ala Asp Glu Asp Glu GGG Thr GGU GUA GUC GUG GUU P. The Y. D Asn spc AUG AUU Glu His Glu Lys Asn Lys Туг H. spc CUU
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