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Genetic Inheritance Patterns Retinitis pigmentosa (RP) can be autosomal recessive, autosomal dominant, or x-linked. Apparently the dominant forms are often less severe. Eric's form of RP is Usher's Syndrome, which is an autosomal recessive inheritance (i.e., you must get a copy of the defective gene from your Mom and one from your Dad). Autosomal means it is not carried on one of the chromosomes that determines sex. Usher's Type II is recessive, so for Eric this means that both his Mom and Dad are carriers of this condition. His brother, Dirk, does not have any symptoms of RP. Question below Imagine you are a genetics counselor, and Dirk, Erik's brother, comes in to see you. Based on his parents, what are Dirk's possible genotypes for RP? What advice would you give Dirk about the chances of Dirk's children having retinitis pigmentosa if his wife is not a carrier? How would your advice change if his wife fully has the disease? Describe all the possibilities, including the percent chances.

Genetic Inheritance Patterns Retinitis pigmentosa (RP) can be autosomal recessive, autosomal dominant, or x-linked. Apparently the dominant forms are often less severe. Eric's form of RP is Usher's Syndrome, which is an autosomal recessive inheritance (i.e., you must get a copy of the defective gene from your Mom and one from your Dad). Autosomal means it is not carried on one of the chromosomes that determines sex. Usher's Type II is recessive, so for Eric this means that both his Mom and Dad are carriers of this condition. His brother, Dirk, does not have any symptoms of RP. Question below Imagine you are a genetics counselor, and Dirk, Erik's brother, comes in to see you. Based on his parents, what are Dirk's possible genotypes for RP? What advice would you give Dirk about the chances of Dirk's children having retinitis pigmentosa if his wife is not a carrier? How would your advice change if his wife fully has the disease? Describe all the possibilities, including the percent chances.

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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**Genetic Inheritance Patterns** Retinitis pigmentosa (RP) can be autosomal recessive, autosomal dominant, or x-linked. Apparently, the dominant forms are often less severe. Eric's form of RP is Usher’s Syndrome, which is an autosomal recessive inheritance (i.e., you must get a copy of the defective gene from your mom and one from your dad). Autosomal means it is not carried on one of the chromosomes that determines sex. Usher’s Type II is recessive, so for Eric this means that both his mom and dad are carriers of this condition. His brother, Dirk, does not have any symptoms of RP. **Question below** Imagine you are a genetics counselor, and Dirk, Eric’s brother, comes in to see you. Based on his parents, what are Dirk’s possible genotypes for RP? What advice would you give Dirk about the chances of Dirk’s children having retinitis pigmentosa if his wife is not a carrier? How would your advice change if his wife fully has the disease? Describe all the possibilities, including the percent chances.
Transcribed Image Text:**Genetic Inheritance Patterns** Retinitis pigmentosa (RP) can be autosomal recessive, autosomal dominant, or x-linked. Apparently, the dominant forms are often less severe. Eric's form of RP is Usher’s Syndrome, which is an autosomal recessive inheritance (i.e., you must get a copy of the defective gene from your mom and one from your dad). Autosomal means it is not carried on one of the chromosomes that determines sex. Usher’s Type II is recessive, so for Eric this means that both his mom and dad are carriers of this condition. His brother, Dirk, does not have any symptoms of RP. **Question below** Imagine you are a genetics counselor, and Dirk, Eric’s brother, comes in to see you. Based on his parents, what are Dirk’s possible genotypes for RP? What advice would you give Dirk about the chances of Dirk’s children having retinitis pigmentosa if his wife is not a carrier? How would your advice change if his wife fully has the disease? Describe all the possibilities, including the percent chances.
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