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- Incomplete penetrance can make autosomal dominant traits skip generations within a family tree. True or False.Cystic fibrosis (CF) is an autosomal recessive trait. A three-generation pedigree is shown below for a family that carries the mutant allele for cystic fibrosis. Note that carriers are not colored in to allow you to figure out their genotypes. Normal allele = F CF mutant allele = f What is the genotype of individual #8?In the pedigree below what type of disease trait expression pattern is being observed? a Autosomal recessive b Autosomal dominant c Y-linked d X-linked recessive e X-linked dominant
- Sickle cell anemia is inherited as an autosomal recessive condition. It also exhibits incomplete dominance in that the heterozygous genotype displays a mild form of the disease known as sickle cell trait while individuals with the homozygous recessive genotype have a severe form of SCA. A man who has severe sickle cell anemia marries a woman who suffers from a mild trait. What is the probabilitu they will have a child with severe SCA?What is the probability they will have a child with mild SCA? What is the probability they will have a normal child? Show ALL work using punnett squares.The trait pictured in the pedigree above could follow either of two of the below inheritance patterns. Which two are they? Y-linked X-linked dominant Autosomal dominant Autosomal recessiveWhat is the most likely inheritance pattern shown in image B, below? B A E KEY Homozygous Homozygous Heterozygous Heterozygous Wild Type Male Female Male Female Male Note: Completely red symbol denotes an individual exhibiting the phenotype of interest CI 11 III IV V 1/4 A Autosomal Dominant Autosomal Recessive Sex-linked Dominant Sex-Linked Recessive Mitochondrial 1/2 1/2 1/2 1/2 Wild Type Female 1/4 1/2 B Affected Known carrier Affected female Normal female Affected male Normal male
- What is the mode of inheritance shown here? Sex-linked recessive Autosomal recessive Autosomal dominant Sex-linked dominantCystic fibrosis (CF) is an autosomal recessive condition triggered by the overproduction of sticky mucus that clogs the lungs and pancreas. It is a life-threatening disease, but medical advances helped the afflicted to live through adulthood. The mother of Claudia died from cystic fibrosis, but her father was normal and never had any relative with CF. Her fiancé, Marcus, turned out to be a carrier of the CF allele. What are the genotypes of Claudia and Marcus? Claudia: ________________________ Marcus: _____________________ They planned to have four children. What is the probability that: a. all children will be normal b. at least two will be normal PLEASE SHOW COMPLETE SOLUTIONCock feathering in chickens is an autosomal recessive trait that is limited to males. List all possible genotypes for the chicken shown in pic (male hen)
- Consider a cross between a Brown furred dog and a Yellow furred dog. All the puppies born from these parents are yellow furred. Crossing the F1 yellow furred sons and F1 yellow furred daughters produces a 3:1 ratio of yellow furred dogs (3) to brown-furred dogs (1) in the F2 generation. True or False: this tells you that brown fur color in this dog species is inherited in an autosomal recessive manner. is it true or false?Please consider the following pedigree. Assume that people who marry in to the family do not carry the allele unless otherwise indicated. Assume complete penetrance. I II 5 6 III 6 IV 1 2 a. Is it possible for the inheritance pattern for the trait illustrated in this pedigree to be as a result of each of the following? Answer yes or no. (i) an autosomal recessive allele (AR) (ii) an autosomal dominant allele (AD) (iii) a X-linked recessive allele (XR) (iv) a X-linked dominant allele (XD) b. Provide a genotype for individual III-6 for the most likely mode of inheritance as determined in (a).Modes of Inheritance for Single Gene Traits • Autosomal Dominant • Autosomal Recessive • X-linked Dominant • X-linked Recessive • Y-linked • Mitochondrial Let us assume that alleles for these traits follow complete dominance.