Fatty acids are converted to their coenzyme A esters in a reversible reaction catalyzed by acyl-CoA synthetase: R-COO +ATP +COA R-C-CoA + AMP + PPi a) The reaction involves two steps the first of which forms an enzyme-bound intermediate identified as the mixed anhydride of the fatty acid and AMP: R-C-O-P-O-nbose-adenine Wite two chemical equations corresponding to the two steps of the reaction catalyzed by the synthetase.
Electron Transport Chain
The electron transport chain, also known as the electron transport system, is a group of proteins that transfer electrons through a membrane within mitochondria to create a gradient of protons that drives adenosine triphosphate (ATP)synthesis. The cell uses ATP as an energy source for metabolic processes and cellular functions. ETC involves series of reactions that convert redox energy from NADH (nicotinamide adenine dinucleotide (NAD) + hydrogen (H)) and FADH2(flavin adenine dinucleotide (FAD)) oxidation into proton-motive force(PMF), which is then used to synthesize ATP through conformational changes in the ATP synthase complex, a process known as oxidative phosphorylation.
Metabolism
Picture a campfire. It keeps the body warm on a cold night and provides light. To ensure that the fire keeps burning, fuel needs to be added(pieces of wood in this case). When a small piece is added, the fire burns bright for a bit and then dies down unless more wood is added. But, if too many pieces are placed at a time, the fire escalates and burns for a longer time, without actually burning away all the pieces that have been added. Many of them, especially the larger chunks or damp pieces, remain unburnt.
Cellular Respiration
Cellular respiration is the cellular process involved in the generation of adenosine triphosphate (ATP) molecules from the organic nutritional source obtained from the diet. It is a universal process observed in all types of life forms. The glucose (chemical formula C6H12O6) molecules are the preferred raw material for cell respiration as it possesses a simple structure and is highly efficient in nature.
![Fatty acids are converted to their coenzyme A esters in a reversible reaction catalyzed by acyl-CoA
synthetase:
R-COO +ATP +COA R-C-COA +AMP + PPi
a) The reaction involves two steps the first of which forms an enzyme-bound intermediate identified as the
mixed anhydride of the fatty acid and AMP:
R-C-O-P-O-nibose-adenine
Write two chemical equations coresponding to the two steps of the reaction catalyzed by the synthetase.
b) The acyl-CoA synthetase reaction as written above is readily reversible. How might the reaction be made
to favor formation of fatty acyl-CoA? Write within the box. Anything outside the box will not be graded.
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