e (x) if the following statements about synthesis of proteins containing an ER sequence are True or False: False i. Translation is initiated by ribosomes located on the ER membrane ii. The signal recognition particle (SRP) binds a sequence of nonpolar (hydrophobic) amino acids. iii. The ER signal sequence may be cleaved by signal peptidase on the cytoplasmic side of the ER membrane. iv. The part of a transmembrane protein that will ultimately be located outside of the cell is inserted into the lumen of the ER during translation. A stop transfer sequence is a series of polar amino acids that halts translocation of a newly synthesized peptide into the ER lumen.

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
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Chapter1: The Human Body: An Orientation
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Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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**Indicate (x) if the following statements about synthesis of proteins containing an ER signal sequence are True or False:**

| True | False |   |
|------|-------|---|
|      |       | i. Translation is initiated by ribosomes located on the ER membrane |
|      |       | ii. The signal recognition particle (SRP) binds a sequence of nonpolar (hydrophobic) amino acids. |
|      |       | iii. The ER signal sequence may be cleaved by signal peptidase on the cytoplasmic side of the ER membrane. |
|      |       | iv. The part of a transmembrane protein that will ultimately be located outside of the cell is inserted into the lumen of the ER during translation. |
|      |       | v. A stop transfer sequence is a series of polar amino acids that halts translocation of a newly synthesized peptide into the ER lumen. |
Transcribed Image Text:**Indicate (x) if the following statements about synthesis of proteins containing an ER signal sequence are True or False:** | True | False | | |------|-------|---| | | | i. Translation is initiated by ribosomes located on the ER membrane | | | | ii. The signal recognition particle (SRP) binds a sequence of nonpolar (hydrophobic) amino acids. | | | | iii. The ER signal sequence may be cleaved by signal peptidase on the cytoplasmic side of the ER membrane. | | | | iv. The part of a transmembrane protein that will ultimately be located outside of the cell is inserted into the lumen of the ER during translation. | | | | v. A stop transfer sequence is a series of polar amino acids that halts translocation of a newly synthesized peptide into the ER lumen. |
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