Answered: In diseases such as Creutzfeldt-Jakob…

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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In diseases such as Creutzfeldt-Jakob disease (CJD), a normal prion protein becomes infectious and transforms other proteins. The "normal" protein and the "infectious" " prion protein are identical in primary structure; that is they are both composed of the same amino acids in the same sequence. What could identify the abnormal protein? 1. The difference could be that the "infectious" protein has undergone a repeated packaging by the Golgi apparatus. 2. The difference could be that the protein has become infected by a bacterium 3. The difference could be that the protein has mutated 4. The difference could be that the "normal" protein's shape; its secondary, tertiary, or possibly quaternary structure has changed.

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