Draw the major product formed for each reaction. (a) The conjugate acid of triethylamine has a pKa -11, the pKa of the most acidic sites of the substrate is ~20. (b) (c) H3C CH3 CH3 H3C. then CH3l H3C Cu-Li ㅅ H3C CH3 then O H3C OCH3 CH3 LDA ++ H3C CH3 then H3C 요. H U-3H 03H

Organic Chemistry
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ISBN:9781305080485
Author:John E. McMurry
Publisher:John E. McMurry
Chapter20: Carboxylic Acids And Nitriles
Section20.SE: Something Extra
Problem 20VC: Electrostatic potential maps of anisole and thioanisole are shown. Which do you think is the...
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Draw the major product formed for each reaction.
(a) The conjugate acid of triethylamine has a pKa -11, the pKa of the most acidic sites of the
substrate is ~20.
(b)
(c)
H3C
CH3
CH3
H3C.
then CH3l
H3C
Cu-Li
ㅅ
H3C
CH3
then O
H3C
OCH3
CH3
LDA
++
H3C
CH3
then
H3C
요.
H
U-3H
03H
Transcribed Image Text:Draw the major product formed for each reaction. (a) The conjugate acid of triethylamine has a pKa -11, the pKa of the most acidic sites of the substrate is ~20. (b) (c) H3C CH3 CH3 H3C. then CH3l H3C Cu-Li ㅅ H3C CH3 then O H3C OCH3 CH3 LDA ++ H3C CH3 then H3C 요. H U-3H 03H
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