Ph Ph CH3 ČH3 Methsuximide Ethosuximide Phensuximide (racemic) (racemic) (racemic) Following is a synthesis of phensuximide. CN Ph CHO + Ph KCN Ph CN CN NaOEt 1. NaOH, H,O H NÓ 2. НС, Н,о COOE 3. heat COOEt COOEL Benzal- Ethyl dehyde cyanoacetate (A) (В) (гасеmie) Ph Ph Ph CH,NH HOOC СООН ELOOC COOEt 'N' (C) (racemic) (D) (racemic) ČH3 Phensuximide (racemic)
Electronic Effects
The effect of electrons that are located in the chemical bonds within the atoms of the molecule is termed an electronic effect. The electronic effect is also explained as the effect through which the reactivity of the compound in one portion is controlled by the electron repulsion or attraction producing in another portion of the molecule.
Drawing Resonance Forms
In organic chemistry, resonance may be a mental exercise that illustrates the delocalization of electrons inside molecules within the valence bond theory of octet bonding. It entails creating several Lewis structures that, when combined, reflect the molecule's entire electronic structure. One Lewis diagram cannot explain the bonding (lone pair, double bond, octet) elaborately. A hybrid describes a combination of possible resonance structures that represents the entire delocalization of electrons within the molecule.
Using Molecular Structure To Predict Equilibrium
Equilibrium does not always imply an equal presence of reactants and products. This signifies that the reaction reaches a point when reactant and product quantities remain constant as the rate of forward and backward reaction is the same. Molecular structures of various compounds can help in predicting equilibrium.
The following three derivatives of succinimide are anticonvulsants that have found use in the treatment of epilepsy, particularly petit mal seizures.
Q. Propose experimental conditions for the conversion of (C) to (D).
![Ph
Ph
CH3
ČH3
Methsuximide
Ethosuximide
Phensuximide
(racemic)
(racemic)
(racemic)
Following is a synthesis of phensuximide.
CN
Ph CHO +
Ph
KCN
Ph
CN
CN
NaOEt
1. NaOH, H,O
H
NÓ
2. НС, Н,о
COOE 3. heat
COOEt
COOEL
Benzal-
Ethyl
dehyde cyanoacetate
(A)
(В)
(гасеmie)
Ph
Ph
Ph
CH,NH
HOOC
СООН
ELOOC
COOEt
'N'
(C)
(racemic)
(D)
(racemic)
ČH3
Phensuximide
(racemic)](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2Fb9589126-4bce-4246-8e7e-106818903ca0%2F5b90387d-8699-45e6-b8e2-8d4fd8b2e09e%2Fcetq42u.jpeg&w=3840&q=75)
![](/static/compass_v2/shared-icons/check-mark.png)
Trending now
This is a popular solution!
Step by step
Solved in 2 steps with 2 images
![Blurred answer](/static/compass_v2/solution-images/blurred-answer.jpg)
![Introduction to General, Organic and Biochemistry](https://www.bartleby.com/isbn_cover_images/9781285869759/9781285869759_smallCoverImage.gif)
![Organic Chemistry](https://www.bartleby.com/isbn_cover_images/9781305080485/9781305080485_smallCoverImage.gif)
![Introduction to General, Organic and Biochemistry](https://www.bartleby.com/isbn_cover_images/9781285869759/9781285869759_smallCoverImage.gif)
![Organic Chemistry](https://www.bartleby.com/isbn_cover_images/9781305080485/9781305080485_smallCoverImage.gif)