Draw the structure of the anti-HIV drug AZT (zidovudine), which stops retro-viral DNA synthesis. When AZT is taken up by cells, it is converted to AZT triphosphate. Explain how this compound could interfere with DNA synthesis

Draw the structure of the anti-HIV drug AZT (zidovudine), which stops retro-viral DNA synthesis. When AZT is taken up by cells, it is converted to AZT triphosphate. Explain how this compound could interfere with DNA synthesis

General, Organic, and Biological Chemistry

7th Edition

ISBN:9781285853918

Author:H. Stephen Stoker

Publisher:H. Stephen Stoker

Chapter22: Nucleic Acids

Section: Chapter Questions

Problem 22.68EP: Suppose that 30% of the nucleotides in a DNA molecule are deoxyguanosine 5'- monophosphate, and that...

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