DNA polymerase 1 has 5' - 3' polymerase activity. 5'-3' exonuclease activity and 3'-5' exonuclease activity necessary for DNA replication. Mutations in the gene that encodes DNA polymerase 1 may cause the enzyme to lose its function. Match the consequence of the lost function mutation to the corresponding lost activity.
Gene Interactions
When the expression of a single trait is influenced by two or more different non-allelic genes, it is termed as genetic interaction. According to Mendel's law of inheritance, each gene functions in its own way and does not depend on the function of another gene, i.e., a single gene controls each of seven characteristics considered, but the complex contribution of many different genes determine many traits of an organism.
Gene Expression
Gene expression is a process by which the instructions present in deoxyribonucleic acid (DNA) are converted into useful molecules such as proteins, and functional messenger ribonucleic (mRNA) molecules in the case of non-protein-coding genes.
DNA polymerase 1 has 5' - 3' polymerase activity. 5'-3' exonuclease activity and 3'-5' exonuclease activity necessary for
Match the consequence of the lost function mutation to the corresponding lost activity.
 alt="Lost 5'-3' polymerase activity
Lost 5'-3' exonuclease activity
no DNA synthesis to fill gaps caused by removing RNA primers
decreased polymerase fidelity
no double helix denaturation
Answer Bank
Lost 3'-5' exonuclease activity
unstable strand separation within the replication bubble
no RNA primer removal during DNA replication
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