Consider the Michaelis-Menten equation and the definition of Km under steady state conditions. Under what conditions will the Km be a measure of substrate binding? v= Vmax [S] / (Km + [S]), where Km = (k2 + k3) / k₁.

Consider the Michaelis-Menten equation and the definition of Km under steady state conditions. Under what conditions will the Km be a measure of substrate binding? v= Vmax [S] / (Km + [S]), where Km = (k2 + k3) / k₁.

Chemistry: The Molecular Science

5th Edition

ISBN:9781285199047

Author:John W. Moore, Conrad L. Stanitski

Publisher:John W. Moore, Conrad L. Stanitski

Chapter11: Chemical Kinetics: Rates Of Reactions

Section: Chapter Questions

Problem 83QRT

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Question

Consider the Michaelis-Menten
equation and the definition of Km under steady
state conditions. Under what conditions will the Km be a measure of substrate
binding?
v= Vmax [S] / (Km + [S]), where Km = (k2 + k3) / k₁.

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