Consider the Michaelis-Menten equation and the definition of Km under steady state conditions. Under what conditions will the Km be a measure of substrate binding? v= Vmax [S] / (Km + [S]), where Km = (k2 + k3) / k₁.
Consider the Michaelis-Menten equation and the definition of Km under steady state conditions. Under what conditions will the Km be a measure of substrate binding? v= Vmax [S] / (Km + [S]), where Km = (k2 + k3) / k₁.
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![Consider the Michaelis-Menten equation and the definition of Km under steady state conditions. Under what conditions will the Km be a measure of substrate binding?
\[ v = V_{\text{max}} [\text{S}] / (K_m + [\text{S}]), \] where \[ K_m = (k_2 + k_3) / k_1. \]](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F4ed96629-5430-48c1-a397-e5c0ff3303b9%2F1331f8be-3acb-4bbb-b7b9-6e6c20fc1d85%2Fnmfn2c_processed.png&w=3840&q=75)
Transcribed Image Text:Consider the Michaelis-Menten equation and the definition of Km under steady state conditions. Under what conditions will the Km be a measure of substrate binding?
\[ v = V_{\text{max}} [\text{S}] / (K_m + [\text{S}]), \] where \[ K_m = (k_2 + k_3) / k_1. \]
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