chloride. Given the (expected) result of the first step of the synthetic sequence, which of these sites is more electrophilic? Does this result make sense, given what you know about the relationship between structure and reactivity? ATTACHED IS THE REACTION WITH THE REACTION PROCEDURE BELOW PROCEDURE To a 125 mL Erlenmeyer flask containing a magnetic stirbar was added 2,6-dimethylaniline (1, 3.0 mL), followed by acetic acid (20 mL). The mixture was stirred until homogeneous and then chloroacetyl chloride (2.0 mL) was added in one portion. Immediately after the addition of chloroacetyl chloride, a concentrated solution of sodium acetate (25 mL) was added in one portion. The mixture was stirred for about five minutes and then DI water (65 mL) was added directly to the reaction mixture in one portion.
Identify all electrophilic sites in chloroacetyl chloride. Given the (expected) result of the first step of the synthetic sequence, which of these sites is more electrophilic? Does this result make sense, given what you know about the relationship between structure and reactivity?
ATTACHED IS THE REACTION WITH THE REACTION PROCEDURE BELOW
PROCEDURE
To a 125 mL Erlenmeyer flask containing a magnetic stirbar was added 2,6-dimethylaniline (1, 3.0 mL), followed by acetic acid (20 mL). The mixture was stirred until homogeneous and then chloroacetyl chloride (2.0 mL) was added in one portion. Immediately after the addition of chloroacetyl chloride, a concentrated solution of sodium acetate (25 mL) was added in one portion. The mixture was stirred for about five minutes and then DI water (65 mL) was added directly to the reaction mixture in one portion.
Step by step
Solved in 2 steps with 1 images
