Anabolic reactions like fatty acid synthesis are inherently endergonic and require exergonic driving forces to proceed forward. Which of the following statements correctly describes the thermodynamics at play in the substrate activation step of fatty acid synthesis and the importance of this step in downstream elongation of the fatty acid chain? (A) Acetyl CoA carboxylase (ACC1) provides free energy that powers the carboxylation of acetyl CoA to form malonyl CoA.(B) The formation of malonyl CoA is powered by the exergonic carboxylation of acetyl CoA.(C) The formation of a b-ketoacyl ACP in the first step of fatty acid synthesis is driven forward because b-ketoacyl synthase hydrolyzes ATP. (D) The addition of two carbons to the growing fatty acid chain is powered by malonyl ACP decarboxylation.(E) Decarboxylation of malonyl ACP is exergonic and the free energy that is released is coupled to ATP synthesis.
Anabolic reactions like fatty acid synthesis are inherently endergonic and require exergonic driving forces to proceed forward. Which of the following statements correctly describes the
(A) Acetyl CoA carboxylase (ACC1) provides free energy that powers the carboxylation of acetyl CoA to form malonyl CoA.
(B) The formation of malonyl CoA is powered by the exergonic carboxylation of acetyl CoA.
(C) The formation of a b-ketoacyl ACP in the first step of fatty acid synthesis is driven forward because b-ketoacyl synthase hydrolyzes ATP.
(D) The addition of two carbons to the growing fatty acid chain is powered by malonyl ACP decarboxylation.
(E) Decarboxylation of malonyl ACP is exergonic and the free energy that is released is coupled to ATP synthesis.
The synthesis of fatty acids mainly palmitic acid from acetyl CoA involves seven enzyme reaction,
In the biosynthesis pathway the condensation reaction is coupled to the hydrolysis of ATP there by driving the reaction to complition. the main process involves two steps:
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