Based on the attached figure (Fig. 18.7B in the textbook), what would anincrease in activation of D1 receptor-expressing spiny neurons in the striatumcause in downstream basal ganglia structures?Direct and indirect pathwaysSubstantiaD1nigraparsD2compacta(transient)Frontal cortexCerebral cortex(transient)+(transient) +(transient)Caudate/putamenVA/VL complexof thalamus(transient)(transient)Globus pallidus,Globus pallidus,external segmentinternal segment0(tonic)(tonic)+(transient)SubthalamicnucleusOA. decreased activity in the globus pallidus external segment (GPeB. decreased activity in the cortexC. increased activity in the subthalamic nucleus (STN)D. decreased activity in the thalamusE. decreased activity in the globus pallidus internal segment (GPI)Parafascicularnucleus

Explanation:The globus pallidus external segment (GPe) would become less active in response to an…

Answered: Based on the attached figure (Fig.…

Human Physiology: From Cells to Systems (MindTap Course List)

9th Edition

ISBN:9781285866932

Author:Lauralee Sherwood

Publisher:Lauralee Sherwood

Chapter7: The Peripheral Nervous System: Efferent Division

Section: Chapter Questions

Problem 8RE

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The therapeutic effect of Aricept (generic donepezil) is due toA: binding of the drug to voltage-gated sodium channels.C: the drug producing an IPSP on the postsynaptic membrane.D: the drug causing the reuptake of acetylcholine at the synapse.E: the drug maintaining higher concentrations of acetylcholine at synapse
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