asic amino acids including lysine. DNA and histones collectively form chromatin. Open open and accessible to the transcriptional machinery than closed chromatin. Histone ciated with open chromatin and occurs near genes that are being actively transcribed. you know about the chemical properties of DNA and the function of histones. whv do tain so many basic amino acids? Answer in no more than two sentences. you know about how acetylation affects lysine, why does histone lysine acetylation oper Answer in one sentence only.

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
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**Transcription:**

Histones contain many basic amino acids including lysine. DNA and histones collectively form chromatin. Open chromatin is much more open and accessible to the transcriptional machinery than closed chromatin. Histone lysine acetylation is associated with open chromatin and occurs near genes that are being actively transcribed.

**Part A:** Given what you know about the chemical properties of DNA and the function of histones, why do histones contain so many basic amino acids? Answer in no more than two sentences.

**Part B:** Given what you know about how acetylation affects lysine, why does histone lysine acetylation open chromatin? Answer in one sentence only.
Transcribed Image Text:**Transcription:** Histones contain many basic amino acids including lysine. DNA and histones collectively form chromatin. Open chromatin is much more open and accessible to the transcriptional machinery than closed chromatin. Histone lysine acetylation is associated with open chromatin and occurs near genes that are being actively transcribed. **Part A:** Given what you know about the chemical properties of DNA and the function of histones, why do histones contain so many basic amino acids? Answer in no more than two sentences. **Part B:** Given what you know about how acetylation affects lysine, why does histone lysine acetylation open chromatin? Answer in one sentence only.
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