After graduating from UNC Charlotte with the BS in Biology, you get a job with an agro-chemical company and are assigned to a lab that is exploring the use of a newly synthesized compound that may be a possible insecticide. The compound is thought to control insect populations by disrupting the genes that control embryonic development. Your lab conducts an experiment to investigate the influence of the compound on developmental genes by measuring the levels of the proteins the genes code for.  You measure protein levels in two groups of insect eggs: the Treatment Group, which is exposed to the compound, and the Control Group, which is exposed to a compound that is known to have no negative effects on gene activity. Your results are shown below. In all graphs, the Control group exhibits normal levels of proteins and gene expression. (Remeber: P > 0.05 means the observed differences are not significant; P < 0.05 means the differences are significant and biologically meaningful).   True or False: 1. The compound affects maternal genes, but has no effect on zygotic genes.  2.   The compound disrupts the establishment of both the dorso-ventral body axis and the anterior-posterior body axis.  3. The compound disrupts the establishment of the dorso-ventral body axis, but does not affect the establishment of the anterior-posterior body axis.

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After graduating from UNC Charlotte with the BS in Biology, you get a job with an agro-chemical company and are assigned to a lab that is exploring the use of a newly synthesized compound that may be a possible insecticide. The compound is thought to control insect populations by disrupting the genes that control embryonic development. Your lab conducts an experiment to investigate the influence of the compound on developmental genes by measuring the levels of the proteins the genes code for.  You measure protein levels in two groups of insect eggs: the Treatment Group, which is exposed to the compound, and the Control Group, which is exposed to a compound that is known to have no negative effects on gene activity. Your results are shown below. In all graphs, the Control group exhibits normal levels of proteins and gene expression. (Remeber: P > 0.05 means the observed differences are not significant; P < 0.05 means the differences are significant and biologically meaningful).

 

True or False:

1. The compound affects maternal genes, but has no effect on zygotic genes.
 2.   The compound disrupts the establishment of both the dorso-ventral body axis and the anterior-posterior body axis.
 3. The compound disrupts the establishment of the dorso-ventral body axis, but does not affect the establishment of the anterior-posterior body axis.

The image contains a grid of nine bar graphs illustrating comparisons between "Treatment" and "Control" groups for various proteins and conditions. Each figure provides a p-value indicating the statistical significance of the difference observed.

1. **Fig. 1: Bicoid**
   - Bars: Treatment (blue) vs. Control (orange)
   - Observation: Control is significantly higher than Treatment.
   - Significance: p < 0.05

2. **Fig. 2: Hunchback**
   - Bars: Treatment (blue) vs. Control (orange)
   - Observation: Control is significantly higher than Treatment.
   - Significance: p < 0.05

3. **Fig. 3: Nanos**
   - Bars: Treatment (blue) vs. Control (orange)
   - Observation: Control is significantly higher than Treatment.
   - Significance: p < 0.05

4. **Fig. 4: Caudal**
   - Bars: Treatment (blue) vs. Control (orange)
   - Observation: Control is significantly higher than Treatment.
   - Significance: p < 0.05

5. **Fig. 5: Dorsal**
   - Bars: Treatment (blue) vs. Control (orange)
   - Observation: Control is significantly higher than Treatment.
   - Significance: p < 0.05

6. **Fig. 6: Gurken**
   - Bars: Treatment (blue) vs. Control (orange)
   - Observation: Control is significantly higher than Treatment.
   - Significance: p < 0.05

7. **Fig. 7: Short Gastrulation**
   - Bars: Treatment (blue) vs. Control (orange)
   - Observation: Control is significantly higher than Treatment.
   - Significance: p < 0.05

8. **Fig. 8: Pair-Rule Proteins**
   - Bars: Treatment (blue) vs. Control (orange)
   - Observation: No significant difference; bars are approximately equal.
   - Significance: p > 0.05

9. **Fig. 9: Segment-Polarity Proteins**
   - Bars: Treatment (blue) vs. Control (orange)
   - Observation: No significant difference; bars are approximately equal.
   - Significance: p > 0.05

Overall, the graphs illustrate that for most proteins and conditions examined
Transcribed Image Text:The image contains a grid of nine bar graphs illustrating comparisons between "Treatment" and "Control" groups for various proteins and conditions. Each figure provides a p-value indicating the statistical significance of the difference observed. 1. **Fig. 1: Bicoid** - Bars: Treatment (blue) vs. Control (orange) - Observation: Control is significantly higher than Treatment. - Significance: p < 0.05 2. **Fig. 2: Hunchback** - Bars: Treatment (blue) vs. Control (orange) - Observation: Control is significantly higher than Treatment. - Significance: p < 0.05 3. **Fig. 3: Nanos** - Bars: Treatment (blue) vs. Control (orange) - Observation: Control is significantly higher than Treatment. - Significance: p < 0.05 4. **Fig. 4: Caudal** - Bars: Treatment (blue) vs. Control (orange) - Observation: Control is significantly higher than Treatment. - Significance: p < 0.05 5. **Fig. 5: Dorsal** - Bars: Treatment (blue) vs. Control (orange) - Observation: Control is significantly higher than Treatment. - Significance: p < 0.05 6. **Fig. 6: Gurken** - Bars: Treatment (blue) vs. Control (orange) - Observation: Control is significantly higher than Treatment. - Significance: p < 0.05 7. **Fig. 7: Short Gastrulation** - Bars: Treatment (blue) vs. Control (orange) - Observation: Control is significantly higher than Treatment. - Significance: p < 0.05 8. **Fig. 8: Pair-Rule Proteins** - Bars: Treatment (blue) vs. Control (orange) - Observation: No significant difference; bars are approximately equal. - Significance: p > 0.05 9. **Fig. 9: Segment-Polarity Proteins** - Bars: Treatment (blue) vs. Control (orange) - Observation: No significant difference; bars are approximately equal. - Significance: p > 0.05 Overall, the graphs illustrate that for most proteins and conditions examined
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