A mutation is found in a tRNA-encoding gene. The wild type (non-mutant) allele (version) produces a tRNA that recognizes the codon GAA, and is charged with the amino acid glutamic acid (Glu). The mutant tRNA is still charged with Glu, but it recognizes the codon UAA. What effect will this have on translation in these cells? How will the proteins produced be different? Speculate: is this mutation more likely to be beneficial or harmful?
Gene Interactions
When the expression of a single trait is influenced by two or more different non-allelic genes, it is termed as genetic interaction. According to Mendel's law of inheritance, each gene functions in its own way and does not depend on the function of another gene, i.e., a single gene controls each of seven characteristics considered, but the complex contribution of many different genes determine many traits of an organism.
Gene Expression
Gene expression is a process by which the instructions present in deoxyribonucleic acid (DNA) are converted into useful molecules such as proteins, and functional messenger ribonucleic (mRNA) molecules in the case of non-protein-coding genes.
A mutation is found in a tRNA-encoding gene. The wild type (non-mutant) allele (version)
produces a tRNA that recognizes the codon GAA, and is charged with the amino acid glutamic
acid (Glu). The mutant tRNA is still charged with Glu, but it recognizes the codon UAA. What
effect will this have on translation in these cells? How will the proteins produced be different?
Speculate: is this mutation more likely to be beneficial or harmful?
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