A mouse fibroblast cell line in culture was treated with a compound derived from a fungus, which caused the cells to stop dividing. In order to understand how this compound inhibits cell division, a culture of these cells was grown and treated with the compound, and cell samples were taken at increasing times after addition of the compound. The cells in each sample were stained with a fluorescent DNA-binding dye and analyzed by flow cytometry. Data are shown below for four cell samples taken at 0, 5, 16, and 24 hours after addition of the compound. Fluorescence intensity is shown on the x-axis and cell number on the y-axis. Cell number Oh 24 h التالي 200 16 h 5 h I 100 200 250 0 100 200 250 0 100 200 200 250 0 100 200 250 Fluorescence In 2-3 sentences, explain which cell cycle phase is blocked by the compound, and how you came to that conclusion.

A mouse fibroblast cell line in culture was treated with a compound derived from a fungus, which caused the cells to stop dividing. In order to understand how this compound inhibits cell division, a culture of these cells was grown and treated with the compound, and cell samples were taken at increasing times after addition of the compound. The cells in each sample were stained with a fluorescent DNA-binding dye and analyzed by flow cytometry. Data are shown below for four cell samples taken at 0, 5, 16, and 24 hours after addition of the compound. Fluorescence intensity is shown on the x-axis and cell number on the y-axis. Cell number Oh 24 h التالي 200 16 h 5 h I 100 200 250 0 100 200 250 0 100 200 200 250 0 100 200 250 Fluorescence In 2-3 sentences, explain which cell cycle phase is blocked by the compound, and how you came to that conclusion.

Biology: The Dynamic Science (MindTap Course List)

4th Edition

ISBN:9781305389892

Author:Peter J. Russell, Paul E. Hertz, Beverly McMillan

Publisher:Peter J. Russell, Paul E. Hertz, Beverly McMillan

Chapter10: Cell Division And Mitosis

Section: Chapter Questions

Problem 1ITD: Biologists have long been interested in the effects of radiation on cells. In one experiment,...

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In order to investigate the cell cycle in HEK293 cells in culture, I ran a flow cytometry experiment. I labeled their nuclei with DAPI to analyze DNA content. In these flow cytometry plots below, label the two main phases of the cell cycle that you can see. Briefly, explain your answer.
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3) Examine the graph showing the relative percentage normal and cancer cells spend in various stages of the cell cycle. Based on the information in the graphs, infer how cancer cells differ from typical, noncancerous cells. Select ALL that apply. A) Cancer cells do not replicate their DNA. B) Cancer cells replicate their DNA too quickly. C) Cancer cells do not go through interphase during their cell cycle. D) Cancer cells spend more time dividing compared to typical cells. E) Cancer cells do not always grow to the same size as typical cells. more than 1 answer. not graded
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