X-linked Recessive InheritanceA gene is described as X-linked when it occurs on the X chromosome and not the Y. Our convention is to indicate X-linkage by attaching theappropriate gene symbol as a superscript on the letter X. Commonly, the wild-type (+) allele is indicated with only a "+" to avoid having totype a superscript on a superscript. For example, a female that is heterozygous and carrying a recessive mutant allele is indicated as X+Xm.Note the convenience of the shorthand + for m+ in this situation. A mutant male has the genotype XmY.When working with X-linked inheritance, always include the X and Y chromosomes in the descriptions of genotypes, and include the sex(male or female) in the descriptions of the phenotypes (e.g., mutant male, wild-type female, etc.). Here are the genotypes and associatedphenotypes for X-linked recessive inheritance:X+X+ Wild-type femaleX+Xm Wild-type femalexmxm Mutant femaleX+YxmyWild-type maleMutant male

Name: X-linked Recessive InheritanceA gene is described as X-linked when it
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Description: X-linked Recessive InheritanceA gene is described as X-linked when it occurs on the X chromosome and not the Y. Our convention is to indicate X-linkage by attaching theappropriate gene symbol as a superscript on the letter X. Commonly, the wild-type

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X-linked Recessive Inheritance
A gene is described as X-linked when it occurs on the X chromosome and not the Y. Our convention is to indicate X-linkage by attaching the
appropriate gene symbol as a superscript on the letter X. Commonly, the wild-type (+) allele is indicated with only a "+" to avoid having to
type a superscript on a superscript. For example, a female that is heterozygous and carrying a recessive mutant allele is indicated as X+Xm.
Note the convenience of the shorthand + for m+ in this situation. A mutant male has the genotype XmY.
When working with X-linked inheritance, always include the X and Y chromosomes in the descriptions of genotypes, and include the sex
(male or female) in the descriptions of the phenotypes (e.g., mutant male, wild-type female, etc.). Here are the genotypes and associated
phenotypes for X-linked recessive inheritance:
X+X+ Wild-type female
X+Xm Wild-type female
xmxm Mutant female
X+Y
xmy
Wild-type male
Mutant male

Expert Solution

Step 1: X-linked inheritance

When a phenotypic expression is predominately seen in male offspring of heterozygous, unaffected mothers, it is known to be an X-linked recessive inheritance. All afflicted males' female children are required carriers.
A daughter with X-linked recessive inheritance receives a single defective gene on the X chromosome from one of her parents. She most likely won't have the genetic disorder because the X chromosome she inherits from the other parent typically cancels out the effect of the mutation.

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