A female is homozygous for a dominant mutation of ACE2 which prevents binding of the spike protein from Covid-19. This woman marries a man that does not contain any mutation for ACE2. Considering the bar body, what would this mean for chances of their daughters being more protected from Covid-19 in the future. What about the sons? Select one: a. Each daughter would have a 50% chance of being essentially immune to Covid 19 due to mosaicism and inactivation of one X. If the X with the wild-type allele for ACE2 is suppressed as the bar body, the women would be more resistant to COVID-19, if the X with the mutant form is suppressed, the daughter have the normal reaction to COVID-19.  Each son will be immune. b. Since the ACE2 receptor has nothing to do with the sex chromosomes, then each daughter will be heterozygous for the mutation and both the sons and daughters will be immune to COVID-19. c. Since females have two X's, each daughter will be twice as affected by COVID-19.

Human Anatomy & Physiology (11th Edition)
11th Edition
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Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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A female is homozygous for a dominant mutation of ACE2 which prevents binding of the spike protein from Covid-19. This woman marries a man that does not contain any mutation for ACE2. Considering the bar body, what would this mean for chances of their daughters being more protected from Covid-19 in the future. What about the sons?

Select one:
a. Each daughter would have a 50% chance of being essentially immune to Covid 19 due to mosaicism and inactivation of one X. If the X with the wild-type allele for ACE2 is suppressed as the bar body, the women would be more resistant to COVID-19, if the X with the mutant form is suppressed, the daughter have the normal reaction to COVID-19.  Each son will be immune.
b. Since the ACE2 receptor has nothing to do with the sex chromosomes, then each daughter will be heterozygous for the mutation and both the sons and daughters will be immune to COVID-19.
c. Since females have two X's, each daughter will be twice as affected by COVID-19.
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