а) Describe the degradation of glycogen, highlighting important enzymes which are involved.

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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а)
Describe the degradation of glycogen, highlighting important enzymes which are involved.
In McArdle's discase, a type of glycogen storage disease, there is a total deficiency of muscle
glycogen phosphorylase. An individual with such disease is not able to exercise strenuously
and experiences muscle cramps. Exercise leads to higher than normal levels of cellular ADP
and Pi. Besides, lactic acid does not accumulate, as in the case of a normal individual. Explain
b)
the chemical imbalances shown in McArdle's discase.
Transcribed Image Text:а) Describe the degradation of glycogen, highlighting important enzymes which are involved. In McArdle's discase, a type of glycogen storage disease, there is a total deficiency of muscle glycogen phosphorylase. An individual with such disease is not able to exercise strenuously and experiences muscle cramps. Exercise leads to higher than normal levels of cellular ADP and Pi. Besides, lactic acid does not accumulate, as in the case of a normal individual. Explain b) the chemical imbalances shown in McArdle's discase.
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