Consider the following original coding sequence of a gene that codes for a short 5- amino acid polypeptide: 5'-ATGGGCTCGAACTCATAA-3' Using the genetic code and the amino acid table below, which of the following sequences arises from a non-conservative missense mutation in the original sequence shown above? First base in codon U C A G U Phe (F) UUU UUC- UUA UUG CUU- CCU CUC CCC CUA CCA CUG- CCG AUU ACU AUC lle (1) ACC AUA- ACA AUG Met (M) start ACG GUU- GCU GUC GCC GUA GCA GUG GCG Leu (L) Leu (L) Second base Val (V) UCU UCC UCA UCG C Ser (S) Pro (P) Thr (T) Ala (A) codon UAU UAC UAA UAG- GAU- GAC- GAA GAG A Tyr (Y) CAU CAC CAAT CAG- AAU AAC AAA AAG STOP His (H) Gln (Q) Asn (N) Lys (K) Asp (D) Glu (E) G UGU UGC UGA STOP UGG Trp (W) CGU CGC CGA CGG AGU AGC AGA AGG GGU GGC GGA GGG Cys (C) Arg (R) Ser (S) Arg (R) Gly (G) U C A G U C A داواolcاد G U C A G U C A G Last base in codon
Consider the following original coding sequence of a gene that codes for a short 5- amino acid polypeptide: 5'-ATGGGCTCGAACTCATAA-3' Using the genetic code and the amino acid table below, which of the following sequences arises from a non-conservative missense mutation in the original sequence shown above? First base in codon U C A G U Phe (F) UUU UUC- UUA UUG CUU- CCU CUC CCC CUA CCA CUG- CCG AUU ACU AUC lle (1) ACC AUA- ACA AUG Met (M) start ACG GUU- GCU GUC GCC GUA GCA GUG GCG Leu (L) Leu (L) Second base Val (V) UCU UCC UCA UCG C Ser (S) Pro (P) Thr (T) Ala (A) codon UAU UAC UAA UAG- GAU- GAC- GAA GAG A Tyr (Y) CAU CAC CAAT CAG- AAU AAC AAA AAG STOP His (H) Gln (Q) Asn (N) Lys (K) Asp (D) Glu (E) G UGU UGC UGA STOP UGG Trp (W) CGU CGC CGA CGG AGU AGC AGA AGG GGU GGC GGA GGG Cys (C) Arg (R) Ser (S) Arg (R) Gly (G) U C A G U C A داواolcاد G U C A G U C A G Last base in codon
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
Related questions
Question
Transcribed Image Text:Consider the following original coding sequence of a gene that codes for a short 5-
amino acid polypeptide:
5'-ATGGGCTCGAACTCATAA-3'
Using the genetic code and the amino acid table below, which of the following
sequences arises from a non-conservative missense mutation in the original
sequence shown above?
First base in codon
U
U
A
UUU
UUC-
UUA
UUG-
CUU
CUC
CUA
CUG-
U
Phe (F)
Leu (L)
Leu (L)
Second base in codon
Val (V)
UCU -
UCC
UCA
UCG
CCU
CCC
CCA
CCG
AUU
ACU-
AUC Ile (1)
ACC
AUA-
ACA
AUG Met (M) start ACG
GUU
GCU-
GUC
GCC
GUA
GCA
GUG
GCG-
C
Ser (S)
Pro (P)
Thr (T)
Ala (A)
UAU
UAC
UAAT
UAG
CAU
CAC
CAA
CAG
AAU
AAC
AAA
AAG
GAU
GAC
GAA
GAG
A
Tyr (Y)
STOP
His (H)
Gln (Q)
Asn (N)
Lys (K)
Asp (D)
Glu (E)
G
UGU
UGC
UGA STOP
UGG Trp (W)
Cys (C)
CGU
CGC
CGA
CGG
AGU
AGC
AGA 1
AGG
GGU-
GGC
GGA
GGG
Arg (R)
Ser (S)
Arg (R)
Gly (G)
U
C
A
G
U
C
A
G
U
C
A
G
U
C
A
G
Last base in codon
Transcribed Image Text:Side chain (R group)
H
H₂N+ C
T
H
-C-0
Glycine
(Gly or G)
O
CH₂
S
CH₂
CH₂
H₂N+ C C-O
H
Methionine
(Met or M)
Serine
(Ser or S)
OH
CH₂
H₂N-C- -C- O
HO
Polar side chains; hydrophilic
O
O
CH₂2₂
H₂N+ C
CH3
H₂N-C-C-0-
но
Alanine
(Ala or A)
OH CH3
CH
H₂N+ C -C -0
I
H
O
H O
Aspartic acid
(Asp or D)
Threonine
(Thr or T)
Electrically charged side chains; hydrophilic
CH₂
H₂N+ C-C
Acidic (negatively charged)
-0-
H O
Phenylalanine
(Phe or F)
H₂N+ C
O
CH₂
CH₂
H₂N+ C
T
H
-0-
H O
Glutamic acid
(Glu or E)
0
SH
CH₂
H₂N+ C -C -0
I
H O
O
Cysteine
(Cys or C)
CH3 CH3
CH
Valine
(Val or V)
NH₂+
CH₂
CH₂2
CH₂
CH₂
H₂N-C-
||
O
H
Lysine
(Lys or K)
CH₂
H₂N+ C-C
|
H O
Tyrosine
(Tyr or Y)
CH3 CH3
CH
CH₂2
H₂N-C-C-0
| ||
HO
OH
CH₂
H₂N-C-C-0
NH
HO
Tryptophan
(Trp or W)
Leucine
(Leu or L)
0
-0- H₂N-C
NH, O
CH₂
H₂N-C
Basic (positively charged)
NH₂
CNH,
NH
CH₂
CH₂
CH₂
HO
Asparagine
(Asn or N)
O
I
H
Arginine
(Arg or R)
-C-0-
H₂C
H₂N+
CH₂
CH₂
H₂C-CH
H₂N-C
CH₂
H O
Isoleucine
(lle or I)
CH₂
с
H O
Proline
(Pro or P)
0 H₂N+
-NH+
-NH
с -0
U=O
0
NH₂
‚_—_—_—_—_—_J_
T
H
0
CH₂
H₂N-C-C-0-
H
Histidine
(His or H)
Glutamine
(Gln or Q)
O
-0
Expert Solution
This question has been solved!
Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.
This is a popular solution!
Trending now
This is a popular solution!
Step by step
Solved in 3 steps
Follow-up Questions
Read through expert solutions to related follow-up questions below.
Follow-up Question
|
|
|
||
|
|
|
||
|
|
|
||
|
|
|
||
|
|
|
Excuse me, the answer you shows to me is not appear in the five options.
Solution
by Bartleby ExpertKnowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Recommended textbooks for you
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:
9780134580999
Author:
Elaine N. Marieb, Katja N. Hoehn
Publisher:
PEARSON
Biology 2e
Biology
ISBN:
9781947172517
Author:
Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:
OpenStax
Anatomy & Physiology
Biology
ISBN:
9781259398629
Author:
McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:
Mcgraw Hill Education,
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:
9780134580999
Author:
Elaine N. Marieb, Katja N. Hoehn
Publisher:
PEARSON
Biology 2e
Biology
ISBN:
9781947172517
Author:
Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:
OpenStax
Anatomy & Physiology
Biology
ISBN:
9781259398629
Author:
McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:
Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)
Biology
ISBN:
9780815344322
Author:
Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher:
W. W. Norton & Company
Laboratory Manual For Human Anatomy & Physiology
Biology
ISBN:
9781260159363
Author:
Martin, Terry R., Prentice-craver, Cynthia
Publisher:
McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)
Biology
ISBN:
9781260231700
Author:
Sylvia S. Mader, Michael Windelspecht
Publisher:
McGraw Hill Education