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5. The image below shows the organization of a type IV protein that resides on the ER membrane. The N- and C-termini of the protein are labeled. Boxes 1 and 2 represent membrane-spanning sequences. Non-membrane-spanning regions of the protein are labeled "X," "Y," and "Z." A stretch of positively-charged amino acids immediately precedes box 1 (arrow head). Starting from the solid black lines below (representing the bilayer), sketch what the topology of the protein would look like once fully translocated (the solid black lines represent the ER phospholipid bilayer). Indicate on your drawing the ER lumen, the cytosol and if boxes 1 and 2 are SA and/or STA sequences. Z 1 2

5. The image below shows the organization of a type IV protein that resides on the ER membrane. The N- and C-termini of the protein are labeled. Boxes 1 and 2 represent membrane-spanning sequences. Non-membrane-spanning regions of the protein are labeled "X," "Y," and "Z." A stretch of positively-charged amino acids immediately precedes box 1 (arrow head). Starting from the solid black lines below (representing the bilayer), sketch what the topology of the protein would look like once fully translocated (the solid black lines represent the ER phospholipid bilayer). Indicate on your drawing the ER lumen, the cytosol and if boxes 1 and 2 are SA and/or STA sequences. Z 1 2

Anatomy & Physiology
Anatomy & Physiology
1st Edition
ISBN:9781938168130
Author:Kelly A. Young, James A. Wise, Peter DeSaix, Dean H. Kruse, Brandon Poe, Eddie Johnson, Jody E. Johnson, Oksana Korol, J. Gordon Betts, Mark Womble
Publisher:Kelly A. Young, James A. Wise, Peter DeSaix, Dean H. Kruse, Brandon Poe, Eddie Johnson, Jody E. Johnson, Oksana Korol, J. Gordon Betts, Mark Womble
Chapter3: The Cellular Level Of Organization
Section: Chapter Questions
Problem 6RQ: Because they are embedded within the membrane, ion channels are examples of ________. receptor...
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5. The image below shows the organization of a type IV protein that resides on the ER membrane. The N- and C-termini of the protein are labeled. Boxes 1 and 2 represent membrane-spanning sequences. Non-membrane-spanning regions of the protein are labeled "X," "Y," and "Z." A stretch of positively-charged amino acids immediately precedes box 1 (arrow head). Starting from the solid black lines below (representing the bilayer), sketch what the topology of the protein would look like once fully translocated (the solid black lines represent the ER phospholipid bilayer). Indicate on your drawing the ER lumen, the cytosol and if boxes 1 and 2 are SA and/or STA sequences. Z 1 2
Transcribed Image Text:5. The image below shows the organization of a type IV protein that resides on the ER membrane. The N- and C-termini of the protein are labeled. Boxes 1 and 2 represent membrane-spanning sequences. Non-membrane-spanning regions of the protein are labeled "X," "Y," and "Z." A stretch of positively-charged amino acids immediately precedes box 1 (arrow head). Starting from the solid black lines below (representing the bilayer), sketch what the topology of the protein would look like once fully translocated (the solid black lines represent the ER phospholipid bilayer). Indicate on your drawing the ER lumen, the cytosol and if boxes 1 and 2 are SA and/or STA sequences. Z 1 2
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