40. Marybeth uses a library of venomous toxins and molecules to test their influence on neuronal firing. Below is a summary of the effects. Predict what type of change would occur to neuronal activity. Toxin 1 Drug Effect Blocks spatial buffering of K+ by astrocytes Alters passive potassium currents by decreasing the permeability of these channels Neuronal activity (Increased or decreased) 2 3 Blocks all glutamatergic receptors 4 Causes the permeability of Cl- to increase at rest? 5 Alters the sensitivity of VG-Na+ channels making them more sensitive to depolarization. 6 Causes the Na/K pump to be more efficient. Bonus Question (optional) 1. Brown-Sequard Syndrome occurs when there is a hemi section of the spinal cord. Predict if a deficit would be observed if there is a hemi section of the right side of the spinal cord at the thoracic level (T11). (1pt each) Observation Using a sharp pin to prick the bottom of the right foot. Lightly stroking the bottom of the left foot. Deficit (yes or no) Asking the patient to wiggle their right toes. Asking the patient to wiggle their finger on the left hand. 2. What exactly are fMRI BLOD signals detecting? How does this relate to neuronal activity? (2 pts) Complete anosmia's often produce changes in a person's behavior and an increased risk in depression. Why
40. Marybeth uses a library of venomous toxins and molecules to test their influence on neuronal firing. Below is a summary of the effects. Predict what type of change would occur to neuronal activity. Toxin 1 Drug Effect Blocks spatial buffering of K+ by astrocytes Alters passive potassium currents by decreasing the permeability of these channels Neuronal activity (Increased or decreased) 2 3 Blocks all glutamatergic receptors 4 Causes the permeability of Cl- to increase at rest? 5 Alters the sensitivity of VG-Na+ channels making them more sensitive to depolarization. 6 Causes the Na/K pump to be more efficient. Bonus Question (optional) 1. Brown-Sequard Syndrome occurs when there is a hemi section of the spinal cord. Predict if a deficit would be observed if there is a hemi section of the right side of the spinal cord at the thoracic level (T11). (1pt each) Observation Using a sharp pin to prick the bottom of the right foot. Lightly stroking the bottom of the left foot. Deficit (yes or no) Asking the patient to wiggle their right toes. Asking the patient to wiggle their finger on the left hand. 2. What exactly are fMRI BLOD signals detecting? How does this relate to neuronal activity? (2 pts) Complete anosmia's often produce changes in a person's behavior and an increased risk in depression. Why
Human Physiology: From Cells to Systems (MindTap Course List)
9th Edition
ISBN:9781285866932
Author:Lauralee Sherwood
Publisher:Lauralee Sherwood
Chapter4: Principles Of Neural And Hormonal Communication
Section: Chapter Questions
Problem 1SQE: Answer the following questions regarding conduction of action potentials using the velocities given...
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Transcribed Image Text:40. Marybeth uses a library of venomous toxins and molecules to test their influence on neuronal firing. Below is a
summary of the effects. Predict what type of change would occur to neuronal activity.
Toxin
1
Drug Effect
Blocks spatial buffering of K+ by astrocytes
Alters passive potassium currents by decreasing the
permeability of these channels
Neuronal activity
(Increased or decreased)
2
3
Blocks all glutamatergic receptors
4
Causes the permeability of Cl- to increase at rest?
5
Alters the sensitivity of VG-Na+ channels making them more
sensitive to depolarization.
6
Causes the Na/K pump to be more efficient.
Bonus Question (optional)
1. Brown-Sequard Syndrome occurs when there is a hemi section of the spinal cord. Predict if a deficit would be
observed if there is a hemi section of the right side of the spinal cord at the thoracic level (T11). (1pt each)
Observation
Using a sharp pin to prick the bottom of the right foot.
Lightly stroking the bottom of the left foot.
Deficit (yes or no)
Asking the patient to wiggle their right toes.
Asking the patient to wiggle their finger on the left hand.
2. What exactly are fMRI BLOD signals detecting? How does this relate to neuronal activity? (2 pts)
Complete anosmia's often produce changes in a person's behavior and an increased risk in depression. Why
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