235) mGluRs are metabotropic receptors that are activated by the binding of the neurotransmitterglutamate. Based on this information, which of the following statements about mGluRs is correct?a. mGluRs open for Cl- ions to flow through in response to activation by glutamate.b. Activation of mGluRs does not result in graded potentials.C. mGluRs activate signaling pathways that act through a second messenger cascade.d. Signal transduction pathways close mGluRs to elicit depolarizations.e.mGluRs are embedded in the membrane of the presynaptic cell.

Answered: 235) mGluRs are metabotropic receptors…

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

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235) mGluRs are metabotropic receptors that are activated by the binding of the neurotransmitter
glutamate. Based on this information, which of the following statements about mGluRs is correct?
a. mGluRs open for Cl- ions to flow through in response to activation by glutamate.
b. Activation of mGluRs does not result in graded potentials.
C. mGluRs activate signaling pathways that act through a second messenger cascade.
d. Signal transduction pathways close mGluRs to elicit depolarizations.
e.
mGluRs are embedded in the membrane of the presynaptic cell.

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glutamate receptors:- membrane have usually two types of glutamate receptors i.e. ionotropic and metabotropic. Ionotropic receptors directly affect the ion channels whereas metabotropic receptors acts directly via G-protein coupled receptors. Metabotropic receptors are classified into 8 groups- mGluR1 to mGluR8.

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