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2. Scientist discovered how cargo proteins traffic in vesicles by making mutations in genes and observing where the cargo protein gets stuck (using either antibodies that detect the cargo or adding a fluorescen tag on the cargo). Below are a list of mutations in particular genes. Mutation #1 in the adaptin protein Mutation #2 in the Cop I coat protein Mutation #3 in the V-snare found in the Vesicle formed at TGN Given the mutation, predict where you will find the lysosomal protein. Indicate whether A. Protein trafficking is not impacted (you find it in the lysosome) B. Protein will be stuck in the TGN C. Protein will be stuck in the vesicle (somewhere between TGN and lysosome)

2. Scientist discovered how cargo proteins traffic in vesicles by making mutations in genes and observing where the cargo protein gets stuck (using either antibodies that detect the cargo or adding a fluorescen tag on the cargo). Below are a list of mutations in particular genes. Mutation #1 in the adaptin protein Mutation #2 in the Cop I coat protein Mutation #3 in the V-snare found in the Vesicle formed at TGN Given the mutation, predict where you will find the lysosomal protein. Indicate whether A. Protein trafficking is not impacted (you find it in the lysosome) B. Protein will be stuck in the TGN C. Protein will be stuck in the vesicle (somewhere between TGN and lysosome)

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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2. Scientist discovered how cargo proteins traffic in vesicles by making mutations in genes and observing where the cargo protein gets stuck (using either antibodies that detect the cargo or adding a fluorescent tag on the cargo). Below are a list of mutations in particular genes. Mutation #1 in the adaptin protein Mutation #2 in the Cop I coat protein Mutation #3 in the V-snare found in the Vesicle formed at TGN Given the mutation, predict where you will find the lysosomal protein. Indicate whether A. Protein trafficking is not impacted (you find it in the lysosome) B. Protein will be stuck in the TGN C. Protein will be stuck in the vesicle (somewhere between TGN and lysosome)
Transcribed Image Text:2. Scientist discovered how cargo proteins traffic in vesicles by making mutations in genes and observing where the cargo protein gets stuck (using either antibodies that detect the cargo or adding a fluorescent tag on the cargo). Below are a list of mutations in particular genes. Mutation #1 in the adaptin protein Mutation #2 in the Cop I coat protein Mutation #3 in the V-snare found in the Vesicle formed at TGN Given the mutation, predict where you will find the lysosomal protein. Indicate whether A. Protein trafficking is not impacted (you find it in the lysosome) B. Protein will be stuck in the TGN C. Protein will be stuck in the vesicle (somewhere between TGN and lysosome)
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