2. If a female with blood type AB mates with a male that has blood type B, what will be the phenotypes of their offspring. (in your answer please make sure to state the ratio of these phenotypes) 3. What A, B blood typing antigens and antibodies do each of the above parents have? |
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- III. LAB REPORT You inherited your blood type from your parents. Your blood type is based on antigens found on your red blood cells named A or B and antibodies found in your plasma called a or b. See Table 1 for the antigen-antibody make-up of different blood types. Table 1 Blood type Antigens Antibodies A A b B B a AB A and B neither a nor b O neither A nor B both a and b A. When would clumping (or agglutination occur? III. LAB REPORT You inherited your blood type from your parents. Your blood type is based on antigens found on your red blood cells named A or B and antibodies found in your plasma called a or b. See Table 1 for the antigen- antibody make-up of different blood types. Table 1 Blood type Antigens Antibodies A A B B a АВ A and B neither a nor b neither A nor B both a and b3. At what age or time in life does an individual acquire the antibodies against ABO antigensother than their own? 4. At what age or time in life does an individual acquire antibodies against Rh positive blood if their own blood type is Rh negative? How do you explain this? 5. Does the vial labeled anti-A antiserum contain whole blood? Explain. What about the vials labeled anti-B and anti-Rh antiserum? 6. What is erythroblastosis fetalis and what is the cause? What blood type must the mother, father and child be in order for this to occur?
- 1. Suppose that the three samples are from two parents and their child. Which individuals are the parents? Which individual is the child? How do you know? Parent 1 = Parents 2 = Child = 2. What genotype must each individual have for this scenario to be possible? Parent 1 = Parent 2 = Child = please answer all of them now.16. The Type A Transferase enzyme, attaches N-acetylgalactosamine (GalNAc) to H-antigen epitopes; the Type B Transferase enzyme instead transfers galactose (Gal) to the H-antigen. Individuals with Type A blood thus have at minimum one copy of the active Type A Transferase, those with Type B have at minimum one copy of the active Type B Transferase, those with Type AB have one active copy of each, those with Type O have neither. Imagine an AB individual who acquires a mutation in their Type B Transferase gene that allows it to be active with either Gal or GalNAc. Make sure to include a brief justification for your answer to each question below. a. What blood type antigens would this individual express? b. If this individual had a child with a normal O partner, what possible blood type antigens could the child express? c. If this individual had a child with a homozygous dominant B partner (BB), what possible blood type antigens could the child express?1.
- 3-4. On the battlefield, a medic is treating a soldier who has lost a great deal of blood. They are out blood typing supplies so the medic, who is Type O negative, simply donates his own blood to the patien What is the possible explanation for this? a. A type O negative person has none of the proteins that can cause rejection in his blood, so his blood can be accepted by anyone. b. A type O do not have antibodies thus cannot make coagulation when mixed with any other blood types. c. It will not work since blood type O- have all the proteins on blood cells that serves as an antigen. d. There is no reference availabie that would support the action of the medic.6. QUESTION #6: In order to better understand the anatomical significance of blood type and the relationship between blood types, complete the below table: Table in which information regarding ABO blood type will be added for this assignment. To which blood From which blood types can an types can an Blood Type Antigen Present Antibody Produced individual with this individual with this blood type blood type receive donate? a donation? A AB7
- 6Figure 42.16 The Rh antigen is found on Rh positive red blood cells. An Rh-negative female can usually carry an Rh-positive fetus to term without difficulty. However, if she has a second Rh-positive fetus, her body may launch an immune attack that causes hemolytic disease of the newborn. Why do you think hemolytic disease is only a problem during the second or subsequent pregnancies?1. Blood Typing Red blood cells are coated in antigens made of glycolipids and glycoproteins. The composition of these molecules is determined by genetics, which have evolved over time. The two most well-known blood groups are the ABO and Rh systems. The surface antigens in the ABO blood group are glycolipids, calied antigen A and antigen B. People with blood type A have antigen A, those with blood type B have antigen B, those with blood type AB have both antigens, and people with blood type O have neither antigen. Antibodies called agglutinogens are found in the blood plasma and react with the A or B antigens, if the two are mixed. When type A and type B blood are combined, agglutination (clumping) of the blood occurs because of antibodies in the plasma that bind with the opposing antigen; this causes clots that coagulate in the kidney causing kidney failure. Type O blood has neither A or B antigens, and therefore, type O blood can be given to all blood types. Type O negative blood is…
