Myasthenia gravis is a chronic autoimmune disorder in which antibodies attack components of the neuromuscular junction. Patients with this condition experience severe muscle weakness and dysfunction resulting in skeletal muscle fatigue, facial drooping, difficulty swallowing, double vision, unsteady walking, and a number of other symptoms. Approximately 90% of patients test positive for antibodies that are reactive to the acetylcholine receptor (AChR). Antibodies targeting the AChR effectively block this receptor, preventing its function. Under homeostatic conditions, explain the role of the AChR in skeletal muscle contraction.

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Immune Disorders

The collaboration between the cells and proteins that work together as a defense system against infection comprises the immune system.Each of them performs a variety of tasks to recognize and/or react against a foreign body.