Myasthenia gravis is a chronic autoimmune disorder in which antibodies attack components of the neuromuscular junction. Patients with this condition experience severe muscle weakness and dysfunction resulting in skeletal muscle fatigue, facial drooping, difficulty swallowing, double vision, unsteady walking, and a number of other symptoms. Approximately 90% of patients test positive for antibodies that are reactive to the acetylcholine receptor (AChR). Antibodies targeting the AChR effectively block this receptor, preventing its function. Under homeostatic conditions, explain the role of the AChR in skeletal muscle contraction.
Myasthenia gravis is a chronic autoimmune disorder in which antibodies attack components of the neuromuscular junction. Patients with this condition experience severe muscle weakness and dysfunction resulting in skeletal muscle fatigue, facial drooping, difficulty swallowing, double vision, unsteady walking, and a number of other symptoms. Approximately 90% of patients test positive for antibodies that are reactive to the acetylcholine receptor (AChR). Antibodies targeting the AChR effectively block this receptor, preventing its function. Under homeostatic conditions, explain the role of the AChR in skeletal muscle contraction.
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Myasthenia gravis is a chronic autoimmune disorder in which antibodies attack components of the neuromuscular junction. Patients with this condition experience severe muscle weakness and dysfunction resulting in skeletal muscle fatigue, facial drooping, difficulty swallowing, double vision, unsteady walking, and a number of other symptoms. Approximately 90% of patients test positive for antibodies that are reactive to the acetylcholine receptor (AChR). Antibodies targeting the AChR effectively block this receptor, preventing its function.
Under homeostatic conditions, explain the role of the AChR in skeletal muscle contraction.
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