2 A researcher is studying the effects of a novel cancer drug on cell division and comparing the new drug to a traditional chemotherapy drug. The traditional drug causes numerous side effects such as nausea, vomiting, hair loss and susceptibility to infections due to low white blood cell counts. The novel drug is a targeted therapy (specifically targets the abnormal protein in the cancer cell) and is likely to reduce side effects that patients experience when treated with traditional chemotherapy. One group of cancer patients was treated with the novel drug and a second group of cancer patients was treated with the traditional chemotherapy drug. Prior and subsequent to treatment, a mitotic index was obtained from a tumor sample from each patient as well as a bone marrow sample (bone marrow cells give rise to all blood cell types including red blood cells and white blood cells). Since this is a double-blind study (neither the patient nor the researcher knows which patients received which drug), the patient samples were labelled with the patients' initials but no information was provided with respect to the drug each patient was receiving. Below is the data for four different patients. Mitotic index was used to measure the effectiveness of each drug treatment. Use the data below to answer the following questions: Patient ID MI bone marrow cells MI bone marrow MI tumor cells MI tumor cells before treatment cells after treatment before treatment after treatment MJ 0.15 0.07 0.44 0.25 JS 0.17 0.15 0.55 0.08 TE 0.14 0.13 0.47 0.05 KR 0.17 0.04 0.51 0.32 b. Which patient(s) do you think were treated with the novel targeted drug therapy? Explain your answer by referencing the data provided in the table.
2 A researcher is studying the effects of a novel cancer drug on cell division and comparing the new drug to a traditional chemotherapy drug. The traditional drug causes numerous side effects such as nausea, vomiting, hair loss and susceptibility to infections due to low white blood cell counts. The novel drug is a targeted therapy (specifically targets the abnormal protein in the cancer cell) and is likely to reduce side effects that patients experience when treated with traditional chemotherapy. One group of cancer patients was treated with the novel drug and a second group of cancer patients was treated with the traditional chemotherapy drug. Prior and subsequent to treatment, a mitotic index was obtained from a tumor sample from each patient as well as a bone marrow sample (bone marrow cells give rise to all blood cell types including red blood cells and white blood cells). Since this is a double-blind study (neither the patient nor the researcher knows which patients received which drug), the patient samples were labelled with the patients' initials but no information was provided with respect to the drug each patient was receiving. Below is the data for four different patients. Mitotic index was used to measure the effectiveness of each drug treatment. Use the data below to answer the following questions: Patient ID MI bone marrow cells MI bone marrow MI tumor cells MI tumor cells before treatment cells after treatment before treatment after treatment MJ 0.15 0.07 0.44 0.25 JS 0.17 0.15 0.55 0.08 TE 0.14 0.13 0.47 0.05 KR 0.17 0.04 0.51 0.32 b. Which patient(s) do you think were treated with the novel targeted drug therapy? Explain your answer by referencing the data provided in the table.
Phlebotomy Essentials
6th Edition
ISBN:9781451194524
Author:Ruth McCall, Cathee M. Tankersley MT(ASCP)
Publisher:Ruth McCall, Cathee M. Tankersley MT(ASCP)
Chapter1: Phlebotomy: Past And Present And The Healthcare Setting
Section: Chapter Questions
Problem 1SRQ
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Nucleic acids are essential biomolecules present in prokaryotic and eukaryotic cells and viruses. They carry the genetic information for the synthesis of proteins and cellular replication. The nucleic acids are of two types: deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). The structure of all proteins and ultimately every biomolecule and cellular component is a product of information encoded in the sequence of nucleic acids. Parts of a DNA molecule containing the information needed to synthesize a protein or an RNA are genes. Nucleic acids can store and transmit genetic information from one generation to the next, fundamental to any life form.
Question
Transcribed Image Text:2. A researcher is studying the effects of a novel cancer drug on cell division and comparing the new drug to
a traditional chemotherapy drug. The traditional drug causes numerous side effects such as nausea,
vomiting, hair loss and susceptibility to infections due to low white blood cell counts. The novel drug is a
targeted therapy (specifically targets the abnormal protein in the cancer cell) and is likely to reduce side
effects that patients experience when treated with traditional chemotherapy. One group of cancer patients
was treated with the novel drug and a second group of cancer patients was treated with the traditional
chemotherapy drug. Prior and subsequent to treatment, a mitotic index was obtained from a tumor sample
from each patient as well as a bone marrow sample (bone marrow cells give rise to all blood cell types
including red blood cells and white blood cells). Since this is a double-blind study (neither the patient nor
the researcher knows which patients received which drug), the patient samples were labelled with the
patients' initials but no information was provided with respect to the drug each patient was receiving. Below
is the data for four different patients. Mitotic index was used to measure the effectiveness of each drug
treatment. Use the data below to answer the following questions:
Patient ID
MI bone marrow cells
MI bone marrow
MI tumor cells
MI tumor cells
before treatment
cells after treatment
before treatment
after treatment
MJ
0.15
0.07
0.44
0.25
JS
0.17
0.15
0.55
0.08
TF
0.14
0.13
0.47
0.05
KR
0.17
0.04
0.51
0.32
b. Which patient(s) do you think were treated with the novel targeted drug therapy? Explain your
answer by referencing the data provided in the table.
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