10. Which of the following statements regarding insulin is false?A. Insulin is a signal that concentrations of blood glucose are high.B. Insulin binding to a cellular receptor initiates a signaling cascade in which thetandem PFK-2 FBPase-2 enzyme is dephosphorylated.C. Insulin leads to activation of PFK-1, promoting glycolysis.D. Insulin leads to activation of glycogen synthase, promoting glycogen synthesis.E. Insulin binds to a specific receptor embedded in the inner membrane of themitochondria.

When blood glucose concentration increases or decreases, carbohydrate metabolism is coordinated by…

Answered: 10. Which of the following statements…

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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15.Which of the following is NOT a second messenger associated with G-proteins? Group of answer choices A.DAG B.GDP C.IP3 D.cAMP E.cGMP
Abnormally low concentrations of (PO4)3- in the bloodstream would trigger which of the following events? A: decreased FGF23 productionC: decreased calcitriol production
Which of the following enzymes does NOT catalyzes the formation a second messenger? A. PI3K B. Protein kinase C C. Phospholipase C D. Guanylyl cyclase Which of the following statements is correct? A. Lipolysis is inhibited by epinephrine and glucagon B. Phosphorylation of triacylglycerol lipase inhibits its activity C. Activation of protein kinase A inhibits lipolysis D. Fatty acids are activated in mitochondria before undergoing b-oxidation E. Lipolysis is stimulated by cAMP F. None of the above
Please provide a good explanation. If the independent variable (IGF-1) is increasing, what would happen to the dependent variable (GHRH)
1A. If Creb upregulates gene T with acetylcholine stimulation, what happens to T when cAMP phosphodiesterase is always active compared to normal? 1B. If Creb normally upregulates expression of gene Y with adrenaline stimulation, what happens to gene Y if PKA has a nonfunctional NLS compared to normal signaling? Choices are: A. Stays the same B. Decreased expression C. Increased expression
Signaling molecules interact with cells through specific macromolec- ular receptors. For each of the four receptors identified below, list all characteristics, by number, which accurately describe that receptor. (a) an adrenergic receptor (b) a steroid receptor . (c) the LDL. receptor_ (d) the insulin receptor 1. Located at the cell surface 2. Associated with the protein clathrin 3. Ligand binding stimulates the activity of phospholipase C 4. A transmembrane protein 5. A DNA-binding protein 6. Located in the cell interior 7. Receptor-ligand complex moves to the lysosome 8. Receptor-ligand complex becomes concentrated in the nucleus 9. Receptor activation can inhibit the synthesis of glycogen 10. The hormone-receptor complex activates specific gene tran- scription 11. Internalization decreases the synthesis of cholesterol esters
Can you explain why it is right and why each answer is wrong
Match the following to the appropriate receptor pathway: Vitamin D Receptor Choose... Heat Shock Protein (HSP) Choose... Growth Factor Receptor Steroid Receptor Family Adenylyl Cyclase (AC) GPCR Thyroid Receptor Family Cytokine Receptor Tyrosine Kinase Domain JAK/STAT Choose... NFKB Choose... G protein Choose... DAG/IP3 pathway Choose...
9. Describe the steps in the G-protein coupled receptor/adenylyl cyclase/CAMP - signaling pathway. What are examples of physiological processes in the body that use this pathway? What are two toxins that activate this pathway and prevent it from being turned off?
In a clinical study, it was found that copaiba essential oil positively regulated multiple signaling pathways in neuronal cells. These included the following signaling pathways which regulate neuronal metabolism, proliferation and immunity: (Select all that apply.) Choose at least one answer. a. AMPK b. pI3K/Akt/mTOR c. MAPK d. JAK/STAT
Define the following terms:a. MTTPb. abetalipoproteinemiac. endogenous lipoprotein pathwayd. PEPCK-Ce. triacylglycerol cycle
6. Increasing the aldosterone secretion during prolonged muscle activity in hot weather allows you to compensate for the sodium loss in sweat and remove the accumulated excess of potassium. Explain these biological effects of the hormone during exercise. For answer: „Total Signal transduction starting with hormon recopios, e) explain the role of the hormone in the regulation of gene transcription and translation; d) describe the role of proteins that have their synthesis regulated by aldosterone.

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