1. As you can see in Fig. 1(C), there is an interaction between A475 on SARS-CoV-2 and S19 on ACE-2. A475 is the amino acid alanine, and S19 is serine. Remember, amino acids form chains through a condensation reaction, as illustrated here: https://chem.libretexts.org/Bookshelves/Introductory Chemistry/Introductory Chemist ry (CK-12)/25%3A Organic Chemistry/25.18%3A Condensation _Reactions). Here are those structures, from Wikipedia: *Copy/paste the link into your browser* Alanine Serine H3C. HO NH, OH NH2 Skeletal formula of L Skeletal formula of L-alanine serine Ball-and-stick model Space-filing model Space-filling model Ball-and-stick model The blue portions of the structure represent nitrogen atoms, and the red portions represent oxygen. The same is true in Figures 1 and 2 in the paper. This interaction is noted to be new to SARS-COV-2 compared to SARS-CoV and is a key finding in explaining how the behaviors of these viruses differ. What kind of interactions could be occurring between A475 and S19? Mark all that apply. A. Dipole-dipole B. London dispersion C. lon-ion D. Hydrogen bond
1. As you can see in Fig. 1(C), there is an interaction between A475 on SARS-CoV-2 and S19 on ACE-2. A475 is the amino acid alanine, and S19 is serine. Remember, amino acids form chains through a condensation reaction, as illustrated here: https://chem.libretexts.org/Bookshelves/Introductory Chemistry/Introductory Chemist ry (CK-12)/25%3A Organic Chemistry/25.18%3A Condensation _Reactions). Here are those structures, from Wikipedia: *Copy/paste the link into your browser* Alanine Serine H3C. HO NH, OH NH2 Skeletal formula of L Skeletal formula of L-alanine serine Ball-and-stick model Space-filing model Space-filling model Ball-and-stick model The blue portions of the structure represent nitrogen atoms, and the red portions represent oxygen. The same is true in Figures 1 and 2 in the paper. This interaction is noted to be new to SARS-COV-2 compared to SARS-CoV and is a key finding in explaining how the behaviors of these viruses differ. What kind of interactions could be occurring between A475 and S19? Mark all that apply. A. Dipole-dipole B. London dispersion C. lon-ion D. Hydrogen bond
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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Concept explainers
Neutral Amino Acids
Amino acids which do not have any charge on them are neutral amino acids.
Globular Protein
The globular proteins refer to the shape of protein specifically spherical in nature apart from spherical form fibrous, disordered and membrane-bound proteins exist. These globular proteins are miscible in water and form a colloidal solution rather than other types which might not exhibit solubility. Many classes of the fold are found in globular proteins, which render them a sphere shape. Globular fold containing proteins usually are referred to by the term globin.
Dimer
Dimers are basic organic compounds, which are derivates of oligomers. It is formed by the combination of two monomers which could potentially be strong or weak and in most cases covalent or intermolecular in nature. Identical monomers are called homodimer, the non-identical dimers are called heterodimer. The method by which dimers are formed is known as “dimerization”.
Dipeptide
A dipeptide is considered a mixture of two distinct amino acids. Since the amino acids are distinct, based on their composition, two dipeptide's isomers can be produced. Various dipeptides are biologically essential and are therefore crucial to industry.
Question
Transcribed Image Text:1. As you can see in Fig. 1(C), there is an interaction between A475 on SARS-CoV-2 and S19
on ACE-2. A475 is the amino acid alanine, and S19 is serine. Remember, amino acids
form chains through a condensation reaction, as illustrated here:
https://chem.libretexts.org/Bookshelves/Introductory Chemistry/Introductory Chemist
ry (CK-12)/25%3A Organic Chemistry/25.18%3A Condensation_ Reactions). Here are
those structures, from Wikipedia:
*Copy/paste the link into your browser*
Alanine
Serine
H3C.
HO
NH,
Skeletal formula of L-
HO
NH2
Skeletal formula of L-alanine
serine
Ball-and-stick model
Space-filling model
Ball-and-stick model
Space-filling model
The blue portions of the structure represent nitrogen atoms, and the red portions represent
oxygen. The same is true in Figures 1 and 2 in the paper. This interaction is noted to be new to
SARS-COV-2 compared to SARS-CoV and is a key finding in explaining how the behaviors of
these viruses differ. What kind of interactions could be occurring between A475 and S19? Mark
all that apply.
A. Dipole-dipole
B. London dispersion
C. lon-ion
D. Hydrogen bond
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