uncatalyzed uncatalyzed uncatalyzed ES EI ES EP (or E•SP (or E-S) E+P Cor E S) P. E+P A ES reaction coordinate

Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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uncatalyzed
uncatalyzed
uncatalyzed
EI
ES
EI
ES
EP
(or E•SP
(or E+S)
(or E+S)
В
ES
reaction
coordinate
Transcribed Image Text:uncatalyzed uncatalyzed uncatalyzed EI ES EI ES EP (or E•SP (or E+S) (or E+S) В ES reaction coordinate
One of the free energy (G)-reaction
coordinate graphs given below
belong to a ligand-binding protein, while
the other two belong to two different
enzymes.
A)Which of the given graphs cannot belong
to an enzyme? A, B or C
Choose one of the options and explain your
reasoning in one or two sentences.
B)What does it mean if an enzyme has
reached catalytic perfection?
means? Which of the graphs of free energy
change given above
Could it belong to a catalytically perfect
enzyme?
C)what kinetic parameter/combination of
parameters an enzyme
shows its efficiency / whether it has
reached catalytic perfection?
D)Which step in the Michaelis-Menten
mechanism is the rate of diffusion?
limited to?
Transcribed Image Text:One of the free energy (G)-reaction coordinate graphs given below belong to a ligand-binding protein, while the other two belong to two different enzymes. A)Which of the given graphs cannot belong to an enzyme? A, B or C Choose one of the options and explain your reasoning in one or two sentences. B)What does it mean if an enzyme has reached catalytic perfection? means? Which of the graphs of free energy change given above Could it belong to a catalytically perfect enzyme? C)what kinetic parameter/combination of parameters an enzyme shows its efficiency / whether it has reached catalytic perfection? D)Which step in the Michaelis-Menten mechanism is the rate of diffusion? limited to?
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