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. BMI (Body mass index) is the ratio mass in kilograms to the square of height in kilograms Between 18 and 25 is normal. Below 18 is low and above 25 is high. You are looking for SNPS that correlate with low BMI. You look at a number of individuals and look at their BMIS And look at several SNPS. Which SNP best correlates with low BMI? BMI 25 16 31 15 26 SNP1 A A A A T SNP2 G G G C C SNP3 T T T C C SNP4 A cl A C A What is exome sequencing? Give an application.

. BMI (Body mass index) is the ratio mass in kilograms to the square of height in kilograms Between 18 and 25 is normal. Below 18 is low and above 25 is high. You are looking for SNPS that correlate with low BMI. You look at a number of individuals and look at their BMIS And look at several SNPS. Which SNP best correlates with low BMI? BMI 25 16 31 15 26 SNP1 A A A A T SNP2 G G G C C SNP3 T T T C C SNP4 A cl A C A What is exome sequencing? Give an application.

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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### SNP and BMI Correlation Analysis #### BMI Definition: - Body Mass Index (BMI) is the ratio of mass in kilograms to the square of height in meters. A BMI between 18 and 25 is considered normal. Below 18 is considered low, and above 25 is high. #### Objective: To find Single Nucleotide Polymorphisms (SNPs) that correlate with low BMI. #### Data Table: | BMI | SNP1 | SNP2 | SNP3 | SNP4 | |-----|------|------|------|------| | 25 | A | G | T | A | | 16 | A | G | T | C | | 31 | A | G | T | A | | 15 | A | C | C | C | | 26 | T | C | C | A | **Question:** Identify the SNP that best correlates with low BMI. --- ### Exome Sequencing #### Definition: Exome sequencing is a genomic technique for sequencing all of the protein-coding regions of genes in a genome, known as the exome. #### Application: One of the key applications is identifying genetic mutations that lead to diseases. --- ### Genetic Pedigree Analysis #### Description: The given pedigree represents an autosomal dominant trait. The goal is to identify the gene responsible by examining variable markers to find associations near the disease gene. #### Pedigree Diagram: - Circles represent females, squares represent males. - Filled symbols indicate individuals with the trait. #### Genetic Marker Table: | Individual | A | B | C | D | E | F | |------------|----|----|----|----|----|----| | 1-1 | 2 | 3 | 1,5| 1,6| 3,7| 2,9| | **1-2** | 3 | 7 | 2,6| 4,5| 4,8| 4,7| | 2-1 | 4,5| 2,6| 3,7| 8,9| 2,6| 1,3| | **2-2** | 3 | 3,6|
Transcribed Image Text:### SNP and BMI Correlation Analysis #### BMI Definition: - Body Mass Index (BMI) is the ratio of mass in kilograms to the square of height in meters. A BMI between 18 and 25 is considered normal. Below 18 is considered low, and above 25 is high. #### Objective: To find Single Nucleotide Polymorphisms (SNPs) that correlate with low BMI. #### Data Table: | BMI | SNP1 | SNP2 | SNP3 | SNP4 | |-----|------|------|------|------| | 25 | A | G | T | A | | 16 | A | G | T | C | | 31 | A | G | T | A | | 15 | A | C | C | C | | 26 | T | C | C | A | **Question:** Identify the SNP that best correlates with low BMI. --- ### Exome Sequencing #### Definition: Exome sequencing is a genomic technique for sequencing all of the protein-coding regions of genes in a genome, known as the exome. #### Application: One of the key applications is identifying genetic mutations that lead to diseases. --- ### Genetic Pedigree Analysis #### Description: The given pedigree represents an autosomal dominant trait. The goal is to identify the gene responsible by examining variable markers to find associations near the disease gene. #### Pedigree Diagram: - Circles represent females, squares represent males. - Filled symbols indicate individuals with the trait. #### Genetic Marker Table: | Individual | A | B | C | D | E | F | |------------|----|----|----|----|----|----| | 1-1 | 2 | 3 | 1,5| 1,6| 3,7| 2,9| | **1-2** | 3 | 7 | 2,6| 4,5| 4,8| 4,7| | 2-1 | 4,5| 2,6| 3,7| 8,9| 2,6| 1,3| | **2-2** | 3 | 3,6|
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