DNA profiling has been used to verify pedigrees of valuable animals such as show dogs, racing greyhounds, and thoroughbred horses. However, the technology is much harder to apply in these cases than it is in forensic applications for humans. In particular, many more DNA markers must be examined in domesticated animals to stablish the identity or close familial relationship of two DNA samples. Why would you need to look at more polymorphic loci in these animals than you would in humans?

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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DNA profiling has been used to verify pedigrees of valuable animals such as show dogs, racing greyhounds, and thoroughbred horses. However, the technology is much harder to apply in these cases than it is in forensic applications for humans. In particular, many more DNA markers must be examined in domesticated animals to stablish the identity or close familial relationship of two DNA samples. Why would you need to look at more polymorphic loci in these animals than you would in humans? 

Expert Solution
Step 1 POLYMORPHIC LOCI

Eukaryotic genomes contain a significant amount of repetitive DNA that does not code for proteins. A portion of this DNA consists of short (1–6 bp) repeats of sequences called short tandem repeats (STRs). STR can be detected by PCR amplification followed by gel electrophoresis Individuals differ in the number of copies of related sequences at a given locus However, we all inherit our profiles from our parents - half from our mother and a half from our father By comparing people's profiles to their probable parents, paternity can be verified. Paternity tests are of great importance in livestock farming. Massey's horse typing service uses this method to confirm a horse's pedigree.

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