Neurons

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University of New Mexico, Main Campus *

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679

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Psychology

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Nov 24, 2024

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docx

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Uploaded by ericavanarsdale

Compare: dementia is an overarching term that refers to a range of symptoms affecting cognitive abilities and Alz and frontal designate the location of dementioa, or what type of deemtia it is. Contrast: Alzheimer's disease usually begins with memory loss, while FTD is typically a behavior or language disorder . Alzheimer’s Is a disease caused by Degeneration of cerebral cortex where Plaques are deposits of a protein fragment called beta-amyloid that build up in the spaces between nerve cells. This occurs due to proteins called tau to detach from microtubules and stick to other tau molecules, forming threads that eventually join to form tangles inside neurons. These tangles block the neuron’s transport system, which harms the synaptic communication between neurons, which harms the synaptic communication between neurons. This has an affect on parts of the brain involved in memory, including the entorhinal cortex and hippocampus. It later affects areas in the cerebral cortex responsible for language, reasoning, and social behavior . Eventually, many other areas of the brain are damaged. The destruction and death of nerve cells causes memory failure, personality changes, problems in carrying out daily activities and other symptoms of Alzheimer’s disease and Over time, all cognitive ability to live independently is dramatically reduced or lost. 3. one hypothesis that explains the development of Alzheimer’s disease is that of Vascular dysfunction. Risk factors associated with higher tau and cerebral beta-amyloid (Aβ) burden are thought to be the culprit for driving progressive cognitive decline in AD is due to accumulation of amyloid-beta (Aβ) and tau proteins. Normal physiology process breaks down and eliminates these proteins, but with Alzheimer that are known to

appear as tangled, hard, insoluble plaques . During a moderate stage of Alzheimer’s, buildup of tau protein causes twists and tangles that can lead to cell structure collapse and a breakdown of the communication between neurons. Over time, the buildup of these proteins goes unabated, and brain cells begin to malfunction. As Alzheimer's disease progresses, more cells become affected and brain tissue shrinks. Is Degeneration of frontal and temporal lobes where Nerve cell damage caused by frontotemporal dementia leads to loss of function in these brain regions, which variably cause deterioration in behavior, personality and/or difficulty with producing or comprehending language and a a group of disorders that occur when nerve cells in the frontal and temporal lobes of the brain are lost. This causes the lobes to shrink and affect behavior, personality, language, and movement. hat different combinations of risk factors in different patients activate the disease in different ways, and that these converge on a common pathway of degeneration. 4.

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