231L Intro to Nuc Sub Reactions TEMPLATE

Draw structures for the carbonyl electrophile and enolate nucleophile that react to give the enone below. 4 D . You do not have to consider stereochemistry. Draw the enolate ion in its carbanion form. . • Draw one structure per sketcher. Add additional sketchers using the drop-down menu in the bottom right corner. Separate multiple reactants using the + sign from the drop-down menu. ChemDoodle 24 O. IF Email fortructor

5. Which of the following is a true statement? A. Electrophile must be electron deficient. B. Steric effect contributes to the SN1 reactivity of tertiary alkyl halides. C. Retention products could be observed in SN2 reaction. D. The nucleophilicity of a species is equal to its basicity. E. Non-polar solvent is suitable for nucleophilic substitution.

Draw structures for the carbonyl electrophile and enolate nucleophile that react to give the enone below. H ax • You do not have to consider stereochemistry. • Draw the enolate ion in its carbanion form. • Draw one structure per sketcher. Add additional sketchers using the drop-down menu in the bottom right corner. • Separate multiple reactants using the + sign from the drop-down menu. 90-85 **** ChomDoodloⓇ Previous Next

ted Write structures for the carbonyl electrophile and enolate nucleophile that react to give the aldol below. ● • You do not have to consider stereochemistry. ● Draw the enolate nucleophile in its carbanion form. • Draw one structure per sketcher. Add additional sketchers using the drop-down menu in the bottom right corner. Separate multiple reactants using the + sign from the drop-down menu. **** 8 OH ? O Sn [F

Please answer all part of the question...thank you

Can you match best nucleophile / conditions from the list that will give a successful hydrolysis reaction for each electrophile? (there's one best nucleophile / conditions for each electrophile)   <List for Nucleophile / condition> a. LiAlH4; hydronium work-up  b. PCC c. NaH d. CrO3 e. HOEt f. H3O+ or OH- g. H2O  h. NaBH4;hydronium work-up    Electrophile 1. Acid chloride 2. Acetic anhydride 3. Ester 4. Amide   I'm asking again on bartleby because pther tutor gave me the right answer because I think I didn't make my question clear enough.

Complete each of the following statements below using the figure below. NaOH a. In the above reaction, [Select ] is the nucleophile. b. In the above reaction, [Select ] is the electrophile. C. In the above reaction, [Select ] is the leaving group. C. The above reaction should proceed via an [ Select ] mechanism.

Can you please help with homework questions. Thank you.

5. Predict the major product of the following reactions. A. + HBr В. HBr C. + H Br 6. Use curved arrows to show to show the mechanism of the reaction C above. Nucleophiles and Electrophiles 7. Label the electrophile and nucleophile in each step of the mechanism for question 6.

Questions 1,3 and 5

Number 1 (a-e)

Why is the mixture placed in an ice-bath during the addition of the concentrated sulfuric acid? (Check all that apply.) MULTIPLE ANSWER A. To avoid the evaporation of the concentrated sulfuric acid. B. To increase the rate of the reaction. C. To favor the formation of the FC alkylation product. D.To reduce the sulfonation of the 1,4-dimethoxybenzene E. To reduce the formation of butene

Which of the following statement about using curved arrows in polar reaction mechanism is true?   a. The nucleophile can be either negatively charged or positively charged. b. The electrophile can be either neutral or positively charged. c. Electrons move from an electrophilic sink to a nucleophilic source. d. None of the above.     a     b     c     d

Draw curved arrows to illustrate the mechanism for the reaction of propanol and HI.

Choose the correct answer from the ff. choices

Preamble: A student chemist in an attempt to synthesise compound B from the aromatic aldehyde.  24. What is the reaction name for the chemical transformation of A to BA. reductive aminationB. catalytic reductionC. carbonyl dehydrationD. Hofmann eliminationE. Aldehyde rearrangement

16. Explain the reaction shown below. Include the following pieces in your explanation. Identify the electrophile and the nucleophile. Draw a curved arrow mechanism for this reaction. (Assume an acidic work-up). Explain the electron flow. Indicate any regiochemical or stereochemical preferences. Ph-0 a. b. c. d. Ph OH

Which statement is true with respect to the directing effects of bromine and methoxy groups in electrophilic aromatic substitution reactions? a.Both Br and OMe are meta directors b.Both Br and OMe are ortho/para directors c. Br is a meta director and OMe are ortho/para directors d.Br is a ortho/para directors and OMe are meta director

Consider the synthetic sequence shown. Identify the reagents for all three steps. Draw the structures of organic compounds A and B. Omit byproducts.

5. In an organic reaction, which of the following is most likely to function as only a nucleophile? a. BF3 b. (CH3)2CH2NH2 с. Fe2+ d. CH3CH2S¯ e. both a and c

ciple Attempts Not allowed. This test can only be taken once. ce Completion Once started, this test must be completed in one sitting. Do not leave the test before clicking Save and Submit This test does not allow backtracking. Changes to the answer after submission are prohibited. emaining Time: 52 minutes, 44 seconds. Question Completion Status: A Moving to the next question prevents changes to this answer. Question 2 Reaction of arenediazonium salts with aryl benzene give.... o Aryl halied Benzonitrile Phenole Azo dayes A Moving to the next question prevents changes to this answer. P Type here to search 1HUAWE F1 F2 F3 F4 F5 F6 F7 %23 24 % & 2 5 6. 7 8. Q W E T Y. us A H. 1S C, Z C VI B U DI

Use curved arrows to draw the mechanisms (pushing electrons) of the following two reactions. Note that each of your mechanisms MUST agree with the description below. 1a.This is a SN2 – 2nd order Nucleophilic substitution mechanism 1b. This is a SN1 – first order Nucleophilic substitution mechanism, you will need to draw two separate chemical equations to indicate the two-step process step 1. step 2. step 3.