231L Alkene Addition TEMPLATE

ciple Attempts Not allowed. This test can only be taken once. ce Completion Once started, this test must be completed in one sitting. Do not leave the test before clicking Save and Submit This test does not allow backtracking. Changes to the answer after submission are prohibited. emaining Time: 52 minutes, 44 seconds. Question Completion Status: A Moving to the next question prevents changes to this answer. Question 2 Reaction of arenediazonium salts with aryl benzene give.... o Aryl halied Benzonitrile Phenole Azo dayes A Moving to the next question prevents changes to this answer. P Type here to search 1HUAWE F1 F2 F3 F4 F5 F6 F7 %23 24 % & 2 5 6. 7 8. Q W E T Y. us A H. 1S C, Z C VI B U DI

4. Circle the electrophilic and nucleophilic atoms in each substitution reaction below. Provide the neutral organic product; where a stereocenter is created, use a wavy bond to indicate a mixture of configurations or wedges/dashes for stereospecific reactions. Also, provide the dominant reaction mechanism (Sn2 or SN1) somewhere in each box. A. Br NaSEt DMF В. ELOH C. .SO2NHNA Cl + D. NaH Br- HO, DMF

How does gold help to catalyze the reaction in the gold catalysis experiment? It deprotonates the methanol, making methanol a better nucleophile. оа. o b. It donates electron density to the alkyne, making the alkyne a better nucleophile. О с. It coordinates to the methanol, making methanol a better nucleophile. o d. It coordinates to the alkyne, making the alkyne a better electrophile.

Which is/are NOT TRUE about bimolecular nucleophilic substitution reactions?  Select one or more: 1. A carbocation intermediate is formed. 2. A strong nucleophile displaces a halogen atom in a concerted mechanism. 3. Presence of polar aprotic solvents promotes this reaction. 4. Methyl halides react faster than secondary alkyl halides.

Question 20 In a unimolecular elimination (E1) reaction, the correct order of mechanistic steps is А. dissociation of the leaving group, then deprotonation at the ß position. simultaneous dissociation of the leaving group and deprotonation of the B position. association of the nucleophile/base, then dissociation of the leaving group. deprotonation at the B position, then dissociation of the leaving group. В. C. D. В O A

Electrophilic aromatic substitutions proceed in two stages. 1. Attack of the aromatic ring on the electrophile. 2. Regeneration of the stable aromatic system by loss of a positively charged unit, usually a proton. Br Br₂/FeBr3 Draw one resonance structure for the intermediate formed when the electrophile is attacked by benzene in the reaction above. • You do not have to consider stereochemistry. • You do not have to explicitly draw H atoms. • Do not include lone pairs in your answer. They will not be considered in the grading.

Circle the electrophilic addition reaction(s) that form(s) a three-membered ring intermediate. a. Addition of hydrogen halides b. Acid-catalyzed addition of water c. Acid-catalyzed addition of alcohols d. Hydroboration-oxidation e. Addition of a halogen f. Addition of a peroxyacid g. Ozonołysis of alkenes h. Addition of hvdrogen

Can you match best nucleophile / conditions from the list that will give a successful hydrolysis reaction for each electrophile? (there's one best nucleophile / conditions for each electrophile)   <List for Nucleophile / condition> a. LiAlH4; hydronium work-up  b. PCC c. NaH d. CrO3 e. HOEt f. H3O+ or OH- g. H2O  h. NaBH4;hydronium work-up    Electrophile 1. Acid chloride 2. Acetic anhydride 3. Ester 4. Amide   I'm asking again on bartleby because pther tutor gave me the right answer because I think I didn't make my question clear enough.

13 saved out of on 14 r saved out of Given the following substitution reaction, what would the effect be of changing the solvent from DMF to CH₂OH? (see NOTE) *NOTE: DMF - NaOCH3 H-C-N(CH3)2 OCH 3 Select one: OA. There would be no effect on the reaction rate. OB. The rate of the reaction would increase. OC. The rate of the reaction would decrease. Clear my choice + Na Br In substitution reactions, (CH3)3C-I reacts at the same rate with Brand CI even though Br is a more reactive nucleophile than Cl. Why? max

5. Predict the major product of the following reactions. A. + HBr В. HBr C. + H Br 6. Use curved arrows to show to show the mechanism of the reaction C above. Nucleophiles and Electrophiles 7. Label the electrophile and nucleophile in each step of the mechanism for question 6.

For each horizontal row of substituted benzenes, indicate a. the one that is the most reactive in an electrophilic aromatic substitution reaction. b. the one that is the least reactive in an electrophilic aromatic substitution reaction. c. the one that yields the highest percentage of meta product in an electrophilic aromatic substitution reaction.

K Question Completion Status: QUESTION 6 Select the missing reagent for the reaction seen below: Cl₂/AIC13 C1₂ ⒸCl₂/FeCl3 HCI QUESTION 7 Salert the miceina raanant from tah raaction echama caan haloue Click Save and Submit to save and submit. Click Save All Answers to save all answers. mercy.blackboard.com F Support ? CI Save All Answ

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LOH NaOH `N' (S) H20 'N' ČI This nucleophilic substitution occurs with rearrangement. Draw curved arrows to show the movement of electrons in the following step of the reaction mechanism. Arrow-pushing Instructions OH :OH N. H.

Show how you might synthesize this compound from an alkyl bromide and a nucleophile in an S№2 reaction. N3 • Use the wedge/hash bond tools to indicate stereochemistry where it exists. • Only draw the reactants. Separate multiple reactants using the + sign from the drop-down menu. • If there is more than one possible combination of alkyl bromide and nucleophile, draw only one combination. • Do not include counter-ions, e.g., Na+, I, in your answer. 90-85 TAYY ? ChemDoodle O OO. #[ ] در

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Choose all correct statements. 1. Gilman reagents react with alkyl halides, including vinyl and aryl halides. 2. Grignard reagents react with alkyl halides, including vinyl and aryl halides. 3. Deprotonation of an alcohol group forms an oxonium intermediate. 4. Whenever a neutral nucleophile attacks, a proton transfer step follows. 5. An alcohol that is chiral at the a-carbon will undergo inversion of absolute configuration when it is converted into an alkyl tosylate. C 1 2 3 4

5. In an organic reaction, which of the following is most likely to function as only a nucleophile? a. BF3 b. (CH3)2CH2NH2 с. Fe2+ d. CH3CH2S¯ e. both a and c

Draw the structure of the alkyl bromide and the nucleophile that will react in an Sy2 reaction to give the product shown. CN Alkyl bromide + Nucleophile H3C • You do not have to consider stereochemistry. Separate multiple reactants using the + sign from the drop-down menu.

Step 4a: Classify step. The target product is present, but the reaction is not over. The ethoxide ion has been regenerated. :0: :0: What is the key process in the next step of the mechanism? proton transfer formation of a o bond between nucleophile and electrophile loss of a leaving group carbocation rearrangement (e.g., methyl or hydride shift)