Experiment 4B

An unknown substance "A" was allowed to partition between a mixture of 150 mL water and 80 mL benzene. After titration, you found that 0.75 moles of "A" was dissolved in the water while 0.60 moles dissolved in benzene. Calculate for the partition coefficient of substance "A". What can you infer about the nature of substance "A" based on the value of the partition coefficient?

You add 1 mL of sample and collect 1 mL fractions from a column with a volume of 20 mL where the beads take up 60% of the column and the protein of interest has a partition coefficient of 0.4. What fraction do you want to keep?

Variation in volume of extraction solvent: compound X is dissolved in 20.0 mL of solvent B. Assuming a partition coefficient of PX,AB of 5.0, calculate the percentage of X that remains in solvent B if it is extracted the following volumes of solvent A:   1.0 mL 10.0 mL 20.0 mL 100.0 mL

At 25 °C, the octanol-water equilibrium partition coefficient KOW of Compound X is 150,000 and its water-gas phase equilibrium partition coefficient KWA is 5000. Estimate the octanol-gas phase equilibrium partition coefficient KOA of Compound X.

Ethyl heptanoate (EH), a food aroma compound, was added to water and allowed to come to equilibrium with a known volume of air and results showed that its partition coefficient, [EHair]/[EHwater] is equal to 1.8 x 10-2. In the same experiment with oil in place of water, its partition coefficient, [EHair]/[EHoi] is found to be lower at 6.0 x 10-6. Account for the difference between the two values.

Partition coefficients (Kow = organic solvent concentration/aqueous concentration, usually reported as log Kow) are important for determining how efficiently organic compounds can be extracted from aqueous solutions. For example, consider the two substances below. Which will be more soluble in water? Hexamethylbenzene (log Kow = 6.41) O Diethyl ether (log Kow = 0.83)

The partition coefficient(k)of a substance between petroleum ether and water is 6. A substance of mass 12 g is dissolved in 50 mL of water. Calculate the total mass of sample that can be extracted into 40 mL of ether if the ether is used in two 20 mL portions.

6. ( If the solubility of solute Z is 1.0 g/60 mL in diethyl ether and is 1.0 g/1110 mL in water. a) Determine the partition coefficient for the solute Z in these two solvents. b) If 60 mg of the solute Z were dissolved in 100 mL of water, how much ether would be required to extract 90% of solute Z in a single extraction. c) What percent of the A would be extracted from the aqueous solution in (b) by two 50 mL portions of ether?

Your group was allocated an unknown substance X and instructed to measure its partition coefficient between an organic solvent and water as part of a lab activity. 4 grams of X are dissolved and shaken in a combination of 130 mL benzene and 100 mL water. Finally, your group identified 0.5 g of X in the benzene layer. Calculate the partition coefficient using the information supplied. What can you tell about substance X's chemical composition?

How would I go about doing this?At 25 °C, the octanol-water equilibrium partition coefficient KOW of Compound X is 150,000 and its water-gas phase equilibrium partition coefficient KWA is 5000. Estimate the octanol-gas phase equilibrium partition coefficient KOA of Compound X.

As part of a lab exercise, your group was assigned an unknown compound X for which you had to determine its partition coefficient between an organic solvent and water. You dissolve and shake 4 grams of X in a mixture of 130 mL benzene and 100 mL of water. At the end, your group discovered that the benzene layer contained 0.5 g of X. Use the information provided to calculate for the partition coefficient. What can you say about the chemical nature of compound X?

substance of mass 10 g is dissolved in 50 mL of water. Calculate the total mass of sample that can be extracted into 40 mL of ether, if the ether is used in two 20 mL portions .The partition coefficient(k)of the substance between petroleum ether and water is give 4

A 78 mg sample of an organic compound (molar mass = 84.0 g/mol) is partitioned between 2.00 mL of water and 2.00 mL of methylene chloride. Separation and processing of the organic phase results in the isolation of 58 mg of the organic compound. Calculate the partition coefficient for the compound between methylene chloride and water (Kpmethylene chloride/water). Your answer should reflect the proper number of significant figures.

You have 150 mL of 0.25 M n-propylamine and you shake this in a mixture of 90 mL of water and 50 mL of an organic solvent and let it achieve equilibrium. You removed the water layer and titrated it using 0.30 M HCl, where end point of the titration was achieved at around 42.5 mL. Calculate for the partition coefficient of n-propylamine and describe the affinity of the compound based on the value you obtain.

c) diethyl ether. After separating the layers, 240 mg of cyclohexanol are recovered from the diethyl ether layer. You approximate that the remaining 10 mg of cyclohexanol must have been dissolved in the aqueous layer. Calculate the partition coefficient. Show work. 250 mg of 1-phenylcyclohexanol are dissolved in a combination of 10 mL of water and 20 mL of

Three extractions with 50 ml portions of chloroform removed 97% of a solute from 200 ml of an aqueous solution. Calculate the partition coefficient of the solute: KD =Cchloro/Caq- Two weak bases (organic amities) have basic dissociation constants of KbA= 1 x 104 and KbB =1 x 10-8. Both bases have partition coefficients of approximately 10 between chloroform and water. Describe a procedure, making use of the difference in K, for separating the two by extraction. Two weak acids, HX and HY, have partition coefficients, Kp = Cet/Caq, of 5 and 50 respectively, and dissociation constants of 1 x 104 and 1 x 108, respectively. Calculate the distribution ratios of the two acids at integral values of pH of the aqueous solution from pH 4 to pH 11, assuming equal volumes of the two solvents. What is the minimum pH for which the ratio of D values is at least 105?

hi, expert please help me with this problem.. i need it before 5 pm thank you As part of a lab exercise, your group was assigned an unknown compound X for which you had to determine its partition coefficient between an organic solvent and water. You dissolve and shake 4 grams of X in a mixture of 130 mL benzene and 100 mL of water. At the end, your group discovered that the benzene layer contained 0.5 g of X. Use the information provided to calculate for the partition coefficient. What can you say about the chemical nature of compound X?  I HAVE 2 ANSWERS  (i don't know if it is correct hehehe) 1st Answer: partition coefficient (Kd)=conc. at 1st phase (C1) / conc. at 2nd phase (C2) Kd = C1/C2 = CH2O / CBenzene Kd = (4g-0.5g) / 100 mL / 0.5G/130 mL Kd = 0.035/0.003846154 Kd = 9.099 or 9.1   (my 1st answer) My 2nd Answer is on the picture please CHECK IF CORRECT. IF NOT PLEASE SEND THE CORRECT ANSWER THANK YOU.

If the solubility of a drug is 3.8g/L and in chloroform 226g/L calculate its partition coefficient to 1 decimal place

Use your knowledge in analytical processes to systematically outline a protocol you will follow to process adulterated palm oil to gain qualitative and quantitative information spectroscopically about any added toxic dye. Explain also the basis for your protocol of choice.

A solution of 3g organic compound X in 200ml of water was extracted with 200 ml of ethyl ether. At equilibrium the concentration of Xin the two phases was ; 2.6g/100ml of ethyl ether ; 0.8g/100 ml of water. Calculate the partition coefficient, Kd, for compound X in the system. Show your calculations and What percentage of the original sample of X was extracted? Show your calculations.

10 Find the transition time of 20g naphthalene with the surrounding temperature as 30oC.Let the boiling tube has mass 25 g, diameter 2.5 cm and thickness 0.15cm. How much time does 30g of ice takes to melt at a surrounding temperature of -50C. (We are using a boiling tube having mass= 20g, radius=1.5cm, thickness=0.2cm.) In the above experiment, let the surrounding temperature is changed to 0oC. What will be the change in the transition time for ice? Repeat the experiment for different surrounding temperatures and study the variation of melting point of ice. Calculate the melting point of wax having a mass 30g. Let we are using a boiling tube of mass 25g, having a thickness 0.5 cm and radius 1.5 cm.( Choose surrounding temperature as 40oC)

please quickly  ,within 1hour thanks ! If it takes longer than an hour, i don't need the answer (3) What are the qualitative and quantitative principles of inductively coupled plasma spectroscopy?

The partition coefficient, Kp, at 25°C (i.e., room temperature) for compound A is 9.71 (for water and benzene). Starting with a solution of 16.6 g of compound A in 110 mL of water, what is the total percent of compound A that is extracted into the benzene after two successive extractions of 65.0 mL benzene each? [Enter a value with 3 sig figs and do not include the % sign]

21.7 mg of this drug were dissolved in 100 mL of buffered water (pH=7.0; T=30) and then  partitioned with octanol portions of 36.5 mL. Calculate how many mg of drug  will remain in water after in the first extraction. partition coefficient = 0.84

2) Assume you are decaffeinating your coffee by extracting the caffeine out with dichloromethane. Your particular brand of coffee contains 100 mg of caffeine in a 200 mL cup of water. The partition coefficient of caffeine in dichloromethane/water is 8.0 (it is more soluble in the dichloromethane).Answer the following questions about how much caffeine would still be in the 200 mL of water based on two different approaches. You should solve this algebraically. If you use an equation found on the internet, you will need to show how it was derived to receive credit.a) How much caffeine would remain in the water after extracting once with 200 mL of dichloromethane? Show your work.b) How much caffeine would remain in the water after extracting twice, each time with 100 mL of dichloromethane? Show your work.