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Which of the following is not considered to be
alive?
Mitochondrion
Chordata are most closely related to
echinodermata
Regarding the tree of life, which of the following
statements is correct?
archaea are more closely related to eukarya than to bacteria
Chemical bonds where electrons are shared
equally are called
non polar covalent bonds
Elemental isotopes result from
a change in the number of neutrons
when one of the atoms involved in a covalent bond
has a higher electronegativity than the other atom,
what is possible about the molecule?
the molecule will be able to make hydrogen bonds
which answer is false concerning valence electrons
they are in the lowest energy state
Which of the following is not a domain of life?
prokaryote
Why are rRNA sequences good for studying
probable evolutionary relationships of all life on the
planet?
all organisms on the planet have rRNA
What contributes to cell theory?
all cells contain DNA, share similar metabolic strategies, come from pre-existing
cells, and are the smallest entities that have all the properties of life
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what is the most abundant element in human cells?
carbon
what is true concerning a property of water?
water has a high specific heat index therefore water can absorb a great deal of
heat resulting in only a small change in temperature
hydrogen bonds can be formed in each of the
following situations except:
between cholesterol and a hydrocarbon chain in an animal membrane
hydrogen bonds can be formed in each of the
following situations
-between nitrogenous bases in a double stranded DNA molecule
-between water and ammonia (NH3)
-between 2 amino acids in an alpha-helix
-between 2 protein subunits interacting in a quaternary structure
what domain do fungi belong to in the universal
tree of life?
eukarya
the tree of life is based on a phylogenetic analysis
of
small subunit ribosomal RNA
an acidic solution has a ___ concentration of protons
and a ___ concentration of hydroxide ions
high, low
you are given 2 chemical bonds to examine, a C-H
bond and a C-O bond. which of the following is
true?
the C-H bonds have more potential energy than C-O bonds
high solubility of alcohol in water is due to the
formation of
hydrogen bonds; hydroxyl group in ethanol allows hydrogen and oxygen atoms in
ethanol molecules to form hydrogen bonds with hydrogen and oxygen atoms of
water molecules
Champerones
allow proteins to assume their proper three dimensional state
the monomeric unit of a protein is a
amino acid
which of the following is FALSE regarding protein
structure?
Van der Waals forces occur between hydrophilic R-groups
what is true regarding protein structure?
-quaternary structure is characterized by bonding between R groups of two or
more polypeptide chains
-denaturation can affect secondary and tertiary structure
-secondary structure is characterized by hydrogen bonding between the carbonyl
and amide groups in the polypeptide
-peptide bonds are poplar covalent bonds
which of the following best summarizes the
relationship between condensation reactions and
hydrolysis reactions?
condensation assembles polymers and hydrolysis breaks down polymers
20 different amino acids are found in the proteins of
cells. What distinguishes these molecules?
the composition of their side chains or R groups
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proteins are denatured by elevated temperatures.
Why are some proteins unable to renature when
cooled?
some proteins require chaperone proteins to refold
What is part of the backbone of an amino acid?
carbon, carboxyl group, amino group
what determines the primary structure of a
polypeptide?
its sequence of amino acids
a peptide bond
is a covalent bond formed between two amino acids
an enzyme requires 2 identical subunits to be active
as an enzyme, thus
that enzyme requires primary, secondary, tertiary and quaternary structure to be
active
what types of amino acids would be most soluble in
water?
those having polar or charged side chains
what types of secondary structures are commonly
found in proteins?
alpha helix and beta pleated sheet
what is false about protein denaturation?
it's always irreversible
what type of interaction is responsible for the
formation of secondary structure of proteins?
hydrogen bonds between portions of the polypeptide backbone
which of the following structures remains constant
when a protein is in its denatured form?
primary
The universal energy currency for the cell is
ATP
exergonic reactions
have negative delta G
Gibb's free energy represents
the energy avaliable to do work
if the pH of a solution becomes lower than what is
optimal for a specific enzyme, what might occur?
the enzyme will denature and become less active
what is false regarding a spontaneous reaction?
free energy of products is greater than free energy of reactants
what is true about a spontaneous reaction?
-reactants are less stable than products
-reactants are more ordered than products
-G is negative
which of the following is not an example of an
energy transformation?
sunlight strikes a prism and separates into distinct wavelengths
which of the following about enzymes is not
correct?
the presence of an enzyme will change the outcome of a reaction
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the second law of thermodynamics states that
one usable form of energy cannot be completely converted into another usable
form
the energy of activation
is the amount of energy required to reach a chemical reaction; transition state
thermal energy is
the kinetic energy of molecular motion, measured as heat
when coal is burned to produce electricity, the
electrical energy produces is less than the potential
energy of the coal. why?
some of the potential energy in the coal is converted into forms of energy other
than electricity
an important adaptation that psychrophilic (cold
loving) enzymes might have is
less rigid tertiary structure so that they maintain the flexibility to carry out their
function
when the temperature is lower than optimal for a
particular enzyme, why does enzyme activity
decrease?
there are fewer collisions between enzyme and reactants; active site is no longer
flexible enough to allow the reaction to proceed
competitive inhibitors
resemble substrate
allosteric activators
bind away from the active site, causing a conformational change in the active site
which of the following would be most likely to
destroy the primary structure of an enzyme
hydrolysis
HIV is a virus that requires the enzyme protease to
complete its life cycle. Protease is inhibited by the
drug Crixivan, which is chemically and structually
similar to the substrate for protease. what is true of
Crixivan?
the effects of Crixivan are decreased by increasing the substrate concentration
which of the following is false about an enzyme
catalyzed reaction in the presence of a competitive
inhibitor?
inhibition is not affected by increasing substrate concentration
which levels of protein organization is correctly
paired with the interaction contributing to that
protein structure?
tertiary structure: Van der waals interactions between hydrophobic amino acids
what is meant when a protein is denatured?
when a protein unfolds
the first law of thermodynamics states that energy
cannot be created or destroyed. for living
organisms, what is an important consequence?
all living organisms must acquire the energy needed for life from their environment
a chemical reaction that has a positive G is best
described as
endergonic
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if most chemical reactions are reversible, what is
one way to ensure that the biochemical reactions in
humans proceed in a forward direction?
products of the reactions are quickly consumed by the next reaction
which of the following is true of a catabolic
reaction?
it leads to increased entropy
a hydrolysis reaction
usually results in increased entropy
you isolated an enzyme from an extremophile that
lived in a 90C hot spring. which of the following is
true about the enzyme?
the enzyme would hav ea lower Km at 90C than 37C
the chemical formula for a six carbon molecule is
C6H12O6. what type of molecule is this?
carbohydrate
which of the following is not part of an RNA
molecule?
thymine
what type of bond holds a T-A pair together in a
DNA molecule?
hydrogen
which of the following is not a function of
carbohydrates?
catalysis
which of the following is true regarding
carbohydrates?
glycogen and starch are composed of alpha glucose polymers
you discover a new species of bacteria whose
genome contains 30% cytosine. how much adenine
does it contain?
20%
occasionally a phospholipid will flip from one side
of the membrane to another. why is this even rare?
it is energetically unfavorable for the polar head group to traverse the
hydrophobic interior of the membrane
which of the following is true of nucleic acid
molecules?
in a double stranded DNA molecule purines hydrogen bond to pyrimidines
molecules with both hydrophilic and hydrophobic
regions are called
amphipathic
what is an appropriate way to describe the plasma
membrane?
selectively permeable, helps maintain homeostasis, fluid not rigid
which of the following is not a component of an
animal plasma membrane?
cellulose
which of the following is true of phospholipids?
they are part of the cell membrane of bacteria
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which of the following molecules does not have a
sugar group?
phospholipid;
nucleic acid, lactose, and cellulose have sugar groups
what is false regarding fatty acids?
unsaturated fatty acids have a higher melting point than saturated fatty acids
saturated fats
are capable of numerous Van der Waals interactions
cholesterol can function as
a stabilizing component of membranes
if the external solution is hypotonic relative to the
inside of a cell, what type of water movement will
occur?
water will move into the cell via osmosis
if a red blood cell is placed in a hypertonic
solution, what will happen?
the red blood cell will shrink
we place human red blood cells into a hypotonic
solution. this means
water will enter the cell, causing it to swell and potentially burst
you have some cells that are growing in a solution
that contains 200nM NaCl. you accidently replace
this salty solution with pure water, what will
happen?
the cells will burst because the inside of the cell is hypertonic (higher salt) relative
to pure water
which of the following correctly describes
secondary active transport of protons and sugar
across a membrane into a cell?
protons move down their concentration gradient while sugar moves against its
concentration gradient
what is one difference between simple and
facilitated diffusion across a cell membrane?
only facilitated diffusion requires an integral membrane protein
what is FALSE regarding the NA+/K+ pump?
it is a symporter
what is TRUE regarding the NA+/K+ pump?
-it requires ATP hydrolysis to work
-it is saturable
-it pumps Na+ out of the cell and K+ into the cell against a concentration gradient
where does the energy come from to power
secondary active transport?
an electrochemical gradient
which of the following moves molecules across a
membrane against a concentration gradient?
active transport
which of the following is an example of primary
active transport?
ATP directly transfers energy to the Na+/K+ pump to transport ions across the
membrane
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which of the following is true regarding the Na+/K+
ATP dependent transporter?
the transporter accepts a phosphate group when ATP is hydrolyzed, causing a
conformational change of the pump
which of the following is TRUE about facilitated
diffusion?
can involved the transport of water through an aquaporin
which of the following is never found in bacterial
cells?
nucleus
which eukaryotic organelle is responsible for
protein sorting and modification?
golgi apparatus
which of the following organelles harnesses energy
in a eukaryotic cell?
mitochondrion
which of the following is not part of mitochondria?
thylakoid membrane
which of the following is not part of the
endomembrane system?
mitochondrion
which of the following is not true of proteins that
get secreted from the cell?
they are transported from the Golgi to the rough endoplasmic reticulum
which of the following is true of proteins that get
secreted from the cell?
-they contain a signal sequence that directs them into the rough ER
-they are transported through the endomembrane system in membrane bound
transport vesicles
-they are synthesized on ribosomes
which of the following correctly pairs the organelle
to its function
Smooth ER; lipid and carbohydrate synthesis
which of the following is true for both prokaryotes
and eukaryotes?
both use ribosomes to synthesize proteins
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