Chapter ST.2, Problem 4RQ

Summary Introduction

To determine: How the bacterial DNA methylation and expression of restriction enzymes are innate defense strategy while the CRISPR/Cas system is adaptive strategy.

Introduction: Bacteria and virus that infects bacteria (bacteriophage) are known to be coevolved and thus have diverse defence mechanisms. Defence strategies are usually fall under two category, one is innate defense and the another is adaptive or acquired defense. Innate immunity is already present in the body whereas adaptive immunity is acquired in life time when exposed to foreign substance.