(a)
Interpretation:
A multi-step synthesis has to be designed for the given conversion.
Concept Introduction:
Target molecule is nothing but the desired product.
Adding
The elimination reaction should be carried out under SN2 condition i.e. with strong nucleophile. So there will be no compensating substitution reaction.
The bulky base is used in the elimination reaction to maximize the amount of elimination product.
To prepare cyclic ether, the
Addition of water to the given starting material creates bifunctional compound.
(b)
Interpretation:
A multi-step synthesis has to be designed for the given conversion.
Concept Introduction:
Target molecule is nothing but the desired product.
Adding
The elimination reaction should be carried out under SN2 condition i.e. with strong nucleophile. So there will be no compensating substitution reaction.
The bulky base is used in the elimination reaction to maximize the amount of elimination product.
To prepare cyclic ether, the alkyl halide and alcohol must be a part of the same molecule.
Addition of water to the given starting material creates bifunctional compound.
(c)
Interpretation:
A multi-step synthesis has to be designed for the given conversion.
Concept Introduction:
Target molecule is nothing but the desired product.
Adding
The elimination reaction should be carried out under SN2 condition i.e. with strong nucleophile. So there will be no compensating substitution reaction.
The bulky base is used in the elimination reaction to maximize the amount of elimination product.
To prepare cyclic ether, the alkyl halide and alcohol must be a part of the same molecule.
Addition of water to the given starting material creates bifunctional compound.
(d)
Interpretation:
A multi-step synthesis has to be designed for the given conversion.
Concept Introduction:
Target molecule is nothing but the desired product.
Adding
The elimination reaction should be carried out under SN2 condition i.e. with strong nucleophile. So there will be no compensating substitution reaction.
The bulky base is used in the elimination reaction to maximize the amount of elimination product.
To prepare cyclic ether, the alkyl halide and alcohol must be a part of the same molecule.
Addition of water to the given starting material creates bifunctional compound.
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Chapter 9 Solutions
EBK ORGANIC CHEMISTRY
- Synthesis pathways for the threearrow_forwarda) Propose a synthesis route to prepare the following product from the given starting material. Note that more than one step reaction is required and you must show all the reaction steps including preparation of the intermediates. OH OHarrow_forwardWhat is the synthesis for a compound below? HO C HOarrow_forward
- Write out the complete forward synthesis of the target molecule below beginning with the precursor shown. Be sure to include all reagents necessary for each reaction step (may require more than one step)arrow_forward5) Show a reasonable synthesis for the following reaction. The reaction can be completed in 3 steps. Draw a reasonable (and complete) mechanism for the first transformation and the last transformation. Name the type of reactions for each step. HO OH OH CHOarrow_forwardWhat sequence of reaction can be used to accomplish the following synthesis? ot H3C CH3 ОН Н охо H3C CH3arrow_forward
- Synthesise the target molecules drawn below using precursor chemicals within the following limitations: 1) ALL intermediates and reagents must be shown.2) Each molecule requires multiple step synthesis.3) You must also synthesize any organometallic reagents or ligands that you wish to use. b) Use any precursor molecules with 7 carbon atoms or less.arrow_forwardSelect the correct reagents to carry out the following multi-step synthesis. CH3 CH2-Br CH,-OH CHO step 1 step 2 step 3 step 4 step 2 NJOH step 3 PCC CHICI, AICI3 step 4 N8S step 1 n the others.arrow_forwardPlease design a synthesis to make the following compounds, each from benzene. You may use any reagents you need, but you must start your synthesis from benzene. O₂N. NO₂ OH NO₂ NH₂ OH OH OHarrow_forward
Organic Chemistry: A Guided InquiryChemistryISBN:9780618974122Author:Andrei StraumanisPublisher:Cengage Learning