The function of the given genes c-myc, PKB, HIF1, and p53 in carcinogenic aerobic glycolysis. Introduction: The carcinogenic cells grow and multiply at a very high rate than normal cells do. This results in the need for quick regenerated energy supply and a large supply of precursor molecules. The ATP (adenosine triphosphate) produced by the process of glycolysis is not capable of meeting the needs of a carcinogenic cell. This results in certain metabolic changesbecause of altered gene expression, which further leads to increased uptake of glucose as well asincreased glycolytic activity in transformed cells.

Question

Want to see the full answer?

Answer 1

Question

Chapter 9, Problem 22RQ

Summary Introduction

To review:

The function of the given genes c-myc, PKB, HIF1, and p53 in carcinogenic aerobic glycolysis.

Introduction:

The carcinogenic cells grow and multiply at a very high rate than normal cells do. This results in the need for quick regenerated energy supply and a large supply of precursor molecules. The ATP (adenosine triphosphate) produced by the process of glycolysis is not capable of meeting the needs of a carcinogenic cell. This results in certain metabolic changesbecause of altered gene expression, which further leads to increased uptake of glucose as well asincreased glycolytic activity in transformed cells.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Students have asked these similar questions

Draw a tripeptide of your choosing at pH 7. Have the N-terminus on the left and the C-terminus on the right. Then: Draw a triangle around the α-carbons. Draw a box around the R-groups. Circle the atoms capable of hydrogen bonding. Highlight the atoms involved in the formation of the peptide bonds. What type of structure have you drawn? (primary, secondary, tertiary or quaternary protein structure).

2. For the flow of fluid over a flat membrane of length 10cm, determine the length-average mass transfer coefficient. The relevant properties of the system are u=0.01cm²/s, D=5 x 106 cm²/s, and v = 5.0 cm/s.

Background Freezing isn't the only challenge in cryopreservation - thawing can be just as difficult. A microwave oven seems like a nice solution, since it deposits energy quickly and microwaves are non-ionizing radiation (they do not cause DNA mutation). However, water absorbs microwaves more effectively than ice does, meaning that the portion of an organ that has already melted will get warmer at a higher rate than the remaining ice – the opposite of what we want! - The transmission of radiation through a weakly absorbing material such as ice or water can be modeled by Beer's law, which assumes that the rate of absorption at a depth x is proportional to the local radiation intensity I(x) times an absorption coefficient, which is often written as μ or a or just µ). Noting that absorption decreases the intensity, we can write a differential equation a Solving the differential equation with the boundary condition on the surface being gives the relationship For a standard microwave oven…