Chapter 8.4, Problem 3LO

Summary Introduction

To write:

Chromosomal rearrangements causing some forms of cancer.

Given:

Chromosomal rearrangements deregulate the gene which causes cancer.

Introduction:

Chromosomal rearrangements in an organism is done by four processes such as deletions, duplications, inversions, and translocations. Inversions and translocations are balanced chromosomal rearrangements in which gene order is changed but do not remove or duplicate gene order. Duplication and deletion are imbalance chromosomal rearrangements in there is loss or addition of a copy of a segment of chromosome.