Genetics: A Conceptual Approach 6E w/ SaplingPlus (Six-Month Access)
Genetics: A Conceptual Approach 6E w/ SaplingPlus (Six-Month Access)
6th Edition
ISBN: 9781319125929
Author: Benjamin A. Pierce
Publisher: W. H. Freeman
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Chapter 8.2, Problem 4COQ
Summary Introduction

To define:

The term haploinsufficiency.

Introduction:

The influence on phenotype depends on the genes located in the deleted region. The chromosome segregation is affected when the deletion involves centromeres region. In homozygous state, the deletions are lethal. However, in individuals who are heterozygous for deletion there can be multiple effects due to various reasons. One of the reasons is haploinsufficiency.

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