The difference between an amorphous and a crystalline solid should be determined.

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Chapter 8, Problem 8.96AP

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Interpretation:

The difference between an amorphous and a crystalline solid should be determined.

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The beta-lactamase hydrolyzes the lactam-ring in penicillin. Describe the mechanism of hydrolysis, insuring to include the involvement of S, D, & K in the reaction sequence. Please help

To map the active site of beta-lactamase, the enzyme was hydrolyzed with trypsin to yield a hexapeptide (P1) with the following amino acids. Glu, Lys, Leu, Phe, Met, and Ser. Treatment of P1 with phenyl isothiocyanate yielded a PTH derivative of phenylalanine and a peptide (P2). Treatment of P1 with cyanogenbromide gave an acidic tetrapeptide (P3) and a dipeptide (P4).Treatment of P2 with 1-fluoro-2,4-dinitrobenzene, followed by complete hydrolysis, yields N-2,4-dinitrophenyl-Glu. P1, P2, and P3 contain the active site serine. Why doesn't D in this hexapeptide not participate in the hydrolysis of the beta-lactam ring even though S, K, and D are involved in the catalyst?

To map the active site of -lactamase, the enzyme was hydrolyzed with trypsin to yield a hexapeptide (P1) with the following amino acids. Glu, Lys, Leu, Phe, Met, and Ser. Treatment of P1 with phenyl isothiocyanate yielded a PTH derivative of phenylalanine and a peptide (P2). Treatment of P1 with cyanogenbromide gave an acidic tetrapeptide (P3) and a dipeptide (P4).Treatment of P2 with 1-fluoro-2,4-dinitrobenzene, followed by complete hydrolysis, yields N-2,4-dinitrophenyl-Glu. P1, P2, and P3 contain the active site serine. Using the experimental results described above derive the primary sequence of the active site hexapeptide. Please help!

Answer 2

Question

Chapter 8, Problem 8.96AP

Interpretation Introduction

Interpretation:

The difference between an amorphous and a crystalline solid should be determined.

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Answer 3

Question

Chapter 8, Problem 8.96AP

Interpretation Introduction

Interpretation:

The difference between an amorphous and a crystalline solid should be determined.

Expert Solution & Answer

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Answer 4

Question

Chapter 8, Problem 8.96AP

Interpretation Introduction

Interpretation:

The difference between an amorphous and a crystalline solid should be determined.

Expert Solution & Answer

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Answer 5

Chapter 8, Problem 8.96AP

Interpretation Introduction

Interpretation:

The difference between an amorphous and a crystalline solid should be determined.

Answer 6

Chapter 8, Problem 8.96AP

Interpretation Introduction

Interpretation:

The difference between an amorphous and a crystalline solid should be determined.

Answer 7

Chapter 8, Problem 8.96AP

Interpretation Introduction

Interpretation:

The difference between an amorphous and a crystalline solid should be determined.

Answer 8

Expert Solution & Answer

Answer 9

Expert Solution & Answer

Answer 10

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Answer 11

Ch. 8.2 - Would you expect the boiling points to increase or...Ch. 8.2 - Prob. 8.3P Ch. 8.2 - Identify the intermolecular forces (dipoledipole,...Ch. 8.4 - Prob. 8.5P Ch. 8.4 - Prob. 8.6P Ch. 8.4 - What evidence is there that global warming is...Ch. 8.4 - Prob. 8.2CIAP Ch. 8.4 - Prob. 8.7P Ch. 8.4 - Prob. 8.8KCP Ch. 8.5 - Prob. 8.3CIAP

The difference between an amorphous and a crystalline solid should be determined.

Solution Summary: The author explains the difference between amorphous and crystalline solids. Crystalline solid particles have flat faces and distinct angles.

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Interpretation:

The difference between an amorphous and a crystalline solid should be determined.

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Chapter 8 Solutions

The difference between an amorphous and a crystalline solid should be determined.

Solution Summary: The author explains the difference between amorphous and crystalline solids. Crystalline solid particles have flat faces and distinct angles.

Videos

Interpretation: The difference between an amorphous and a crystalline solid should be determined.

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Chapter 8 Solutions

Interpretation:

The difference between an amorphous and a crystalline solid should be determined.