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To discuss:
Effects of dietary vitamins A, C, and D on bone
Introduction:
Mineralization is a process (crystallization) that deposits phosphate, calcium, and other ions (from blood plasma) in the tissues of the bone as hydroxyapatite. This process is initiated by the osteoblast by laying collagen fibers on the surface of the osteon. These fibers are coated with minerals that make the matrix hard. Only if the concentration of the products (of above minerals) in the plasma reaches the critical value (solubility product), the hydroxyapatite is formed. Sometimes, calcification is repressed by some inhibitors found in the tissue. This inhibitor is deactivated by osteoblast, and it enables the precipitation of the salt in the matrix of the bone. The initially formed crystals perform like a “seed of crystals” that attract more phosphate and calcium from the plasma.
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Chapter 7 Solutions
ANATOMY+PHYSIOLOGY,VOL.2 >CUSTOM<
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- KD 200- 116- 66- Vec ATF6 (670) ATF6 (402) ATF6 (373) ATF6 (366) I I 45- 1 2 3 4 5 ATFG (360) (e/c) 9V ATFG (402) g ant- ATF anti-KDEL DAPI barrow_forwardWestern blot results: what information can you get? Presence of proteins of your interest Levels of protein expression Levels of protein activation (must use activation state-specific antibody) Decreased function of the ATM kinase in aging mice. A C57BL/6 female 6 month Con IR 20 month C57BL/6 male 6 month 28 month Con IR Con IR Con IR p-ATM (S1981) ATM P-p53 (ser18) Actinarrow_forwardDoes it show the level of proteins? What about the amount? Levels of protein activation? How can you tell? Does the thickness tell you anything? What about the number of the lines?arrow_forward
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