Hole's Essentials of Human Anatomy & Physiology
13th Edition
ISBN: 9781259277368
Author: David N. Shier Dr., Jackie L. Butler, Ricki Lewis Dr.
Publisher: McGraw-Hill Education
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Chapter 7, Problem 6CA
Summary Introduction
A substance that forms the skeleton of the body is known as a bone. It is a rigid organ that is found to be composed of bone tissues. It provides structure and support to the body, protects various organs, stores minerals, enables motility, and produces red and white blood cells.
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1. In vivo testing provides valuable insight into a drug’s kinetics. Assessing drug kinetics following multiple different routes of administration provides greater insight than just a single route of administration alone. The following data was collected in 250 g rats following bolus iv, oral (po), and intraperitoneal (ip) administration.Using this data and set of graphs, determine:
(a) k, C0, V, and AUC* for the bolus iv data (b) k, ka, B1, and AUC* for the po data (c) k, ka, B1, and AUC* for the ip data (d) relative bioavailability for po vs ip, Fpo/Fip (e) absolute po bioavailability, (f)Fpo absolute ip bioavailability, Fip
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Chapter 7 Solutions
Hole's Essentials of Human Anatomy & Physiology
Ch. 7.1 - List the active tissues found in a bone.
Ch. 7.1 - Prob. 1PCh. 7.2 - Describe the macroscopic and microscopic structure...Ch. 7.2 - Explain how bones are classified by shape.
Ch. 7.2 - List five major parts of a long bone.
Ch. 7.2 - How do compact and spongy bone differ in...Ch. 7.2 - Describe the microscopic structure of compact...Ch. 7.3 - Distinguish between intramembranous and...Ch. 7.3 - Prob. 6PCh. 7.3 - Explain how an endochondral bone develops.
Ch. 7.3 - Explain how osteoclasts and osteoblasts remodel...Ch. 7.3 - Explain how nutritional factors, hormones, and...Ch. 7.4 - Discuss the major functions of bones.
Ch. 7.4 - Name the major functions of bones.
Ch. 7.4 - Distinguish between the functions of red marrow...Ch. 7.4 - List the substances normally stored in bone...Ch. 7.4 - Prob. 1QCh. 7.5 - Distinguish between the axial and appendicular...Ch. 7.5 - Distinguish between the axial and appendicular...Ch. 7.5 - List the bones of the axial skeleton and of the...Ch. 7.6 - Locate and identify the bones and the major...Ch. 7.6 - Locate and name each of the bones of the...Ch. 7.6 - Locate and name each of the facial bones.
Ch. 7.6 - Explain how an adult skull differs from that of an...Ch. 7.7 - Locate and identify the bones and the major...Ch. 7.7 - Describe the structure of the vertebral column.
Ch. 7.7 - Describe a typical vertebra.
Ch. 7.7 - Explain how the structures of cervical, thoracic,...Ch. 7.8 - Locate and identify the bones and the major...Ch. 7.8 - Which bones compose the thoracic cage?
Ch. 7.8 - Prob. 22PCh. 7.8 - Prob. 23PCh. 7.9 - Prob. 9LCh. 7.9 - Prob. 24PCh. 7.9 - Prob. 25PCh. 7.10 - Locate and identify the bones and the major...Ch. 7.10 - Prob. 26PCh. 7.10 - Prob. 27PCh. 7.11 - Locate and identify the bones and the major...Ch. 7.11 - Prob. 28PCh. 7.11 - Prob. 29PCh. 7.11 - Prob. 1QCh. 7.12 - Prob. 12LCh. 7.12 - Locate and name each of the bones of the lower...Ch. 7.12 - Prob. 31PCh. 7.12 - Prob. 32PCh. 7.13 - Prob. 13LCh. 7.13 - Prob. 14LCh. 7.13 - Prob. 15LCh. 7.13 - Prob. 33PCh. 7.13 - Prob. 34PCh. 7.13 - Prob. 35PCh. 7 - Prob. 1CACh. 7 - Sketch a typical long bone, and label its...Ch. 7 - Discuss the functions of the parts labeled in the...Ch. 7 - Distinguish between the microscopic structure of...Ch. 7 - Prob. 5CACh. 7 - _____ are mature bone cells, whereas _____ are...Ch. 7 - Prob. 7CACh. 7 - Prob. 8CACh. 7 - Prob. 9CACh. 7 - Prob. 10CACh. 7 - Prob. 11CACh. 7 - Prob. 12CACh. 7 - Prob. 13CACh. 7 - Prob. 14CACh. 7 - Prob. 15CACh. 7 - Prob. 16CACh. 7 - Prob. 17CACh. 7 - Prob. 18CACh. 7 - Prob. 19CACh. 7 - Prob. 20CACh. 7 - Prob. 21CACh. 7 - Prob. 1IACTCh. 7 - Prob. 2IACTCh. 7 - Prob. 3IACTCh. 7 - Prob. 4IACT
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