Human Biology: Concepts and Current Issues (8th Edition)
8th Edition
ISBN: 9780134042435
Author: Michael D. Johnson
Publisher: PEARSON
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Textbook Question
Chapter 7, Problem 3CR
Explain how the production of red blood cells is regulated to maintain homeostasis of the oxygen-
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Digoxin: Intravenous Bolus - Two Compartment Model
Drug
Digoxin
Route:
IV Bolus
Dose:
0.750 mg
Plasma Concentration Time Profile
Beta
Alpha
Time (hrs)
Conc (ng/ml)
LN
(ng/ml)
LN
(ng/ml)
LN
0.00
#NUM!
#NUM!
#NUM!
0.10
12.290
2.509
#NUM!
#NUMI
0.60
6.975
1.942
#NUM!
#NUMI
1.00
4.649
1.537
#NUM!
#NUMI
2.00
2.201
0.789
#NUM!
#NUM!
3.00
1.536
0.429
#NUM!
#NUM!
4.00
1.342
0.294
#NUM!
#NUM!
5.00
1.273
0.241
#NUM!
#NUMI
6.00
1.238
0.213
#NUM!
#NUM!
7.00
1.212
0.192
#NUM!
#NUM!
8.00
1.188
0.172
#NUMI
#NUM!
9.00
1.165
0.153
#NUM!
#NUMI
10.00
1.143
0.134
#NUMI
#NUM!
11.00
1.122
0.115
#NUM!
12.00
1.101
0.096
#NUMI
13.00
1.080
0.077
#NUMI
16.00
1.020
0.020
#NUMI
24.00
0.876
-0.132
#NUMI
Pharmacokinetic Parameters
Parameter
Value
Alpha
B
Beta
Units
ng/ml
hr-1
ng/ml
hr-1
CO
ng/ml
H.C
AUC
ng x hr/ml
Vc
Vbeta
Vss
C
L/hr
TK (alpha)
hr
TX (beta)
days
5+
F3
F4
F5
0+
F6
F7
%
6
95
14
#3
29
&
t
F8
F9
FW
EW
Chapter 7 Solutions
Human Biology: Concepts and Current Issues (8th Edition)
Ch. 7 - Prob. 1QCCh. 7 - Prob. 2QCCh. 7 - Describe the functions of blood.Ch. 7 - Prob. 2CRCh. 7 - Explain how the production of red blood cells is...Ch. 7 - Prob. 4CRCh. 7 - Prob. 5CRCh. 7 - Prob. 6CRCh. 7 -
7. Describe the mechanism of hemostasis.
Ch. 7 - Prob. 8CR
Ch. 7 - Prob. 9CRCh. 7 - Prob. 10CRCh. 7 - Prob. 1TYCh. 7 - Prob. 2TYCh. 7 - Prob. 3TYCh. 7 - Prob. 4TYCh. 7 - Prob. 5TYCh. 7 -
6. A person with Type A- (A-negative) blood will...Ch. 7 - Prob. 7TYCh. 7 - Prob. 8TYCh. 7 - Prob. 9TYCh. 7 - Prob. 10TYCh. 7 -
11. Which white blood cells are present in the...Ch. 7 - Prob. 12TYCh. 7 - Prob. 13TYCh. 7 - Prob. 14TYCh. 7 - Prob. 15TYCh. 7 - Prob. 1AWKCh. 7 - Prob. 2AWKCh. 7 - Prob. 3AWKCh. 7 - Prob. 4AWKCh. 7 - Prob. 5AWKCh. 7 -
6. Coumadin is an anticoagulant drug that is...
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