Microbiology: Principles and Explorations
9th Edition
ISBN: 9781118743164
Author: Jacquelyn G. Black, Laura J. Black
Publisher: WILEY
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Textbook Question
Chapter 7, Problem 20SQ
Name and describe the effects of the following mutations (read from left of right):
- (a) ______________________________
- (b) ______________________________
- (c) ______________________________
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Describe any 5 types of mutation (except to loss of function and gain of function). Use 5 sentences only
Determine the effect of the following mutations on the DNA sequence. In each case, the mutation is described after the sequence (REFER TO THE SUPPLEMENTAL DOCUMENT FOR GUIDANCE TO THIS QUESTION).
Guanine nucleotide (G shown in red below) was deleted from the DNA sequence at the position indicated by the arrow). Write out the sequence of the mutated DNA and the protein made from it. What is the effect of this mutation on the protein? (For example, how will the mutation affect the length and sequence of the protein? What about the function of the protein?)
Explain the genetic alterations resulting in protein synthesis defects and their relationship to disease processes such as sickle cell anemia and polycystic kidney disease.
Chapter 7 Solutions
Microbiology: Principles and Explorations
Ch. 7 - Compare and contrast chromosomes in prokaryotes...Ch. 7 - DNA is not always the gemetic material. What are...Ch. 7 - How could mutations give rise to new alleles of a...Ch. 7 - How does trandlation differ from transcription?Ch. 7 - Distinguish between leading and lagging strands.Ch. 7 - What do 5 and 3 refer to? How do they determine...Ch. 7 - Contrast the three kinds of RNA. Does DNA make all...Ch. 7 - What feeds back in feedback inhibition? What does...Ch. 7 - What is the inducer for the lac operon?Ch. 7 - Compare enzyme induction and enzyme repression.
Ch. 7 - If you had be exposed to a mutagen,would you...Ch. 7 - How can a change in geneotype fail to produce a...Ch. 7 - Why are nitrates and nitrites, which have been...Ch. 7 - Cathy develops a painful cluster of blister-like...Ch. 7 - Prokaryotes usually have just one chromosome and...Ch. 7 - During the early stages of development of the...Ch. 7 - Suppose you are a medical technician working in a...Ch. 7 - Match the following terms with their descriptions:Ch. 7 - Prob. 2SQCh. 7 - Prob. 3SQCh. 7 - Match the following terms with their respective...Ch. 7 - From the DNA template sequence 3-ATGCAGTAG-5, what...Ch. 7 - What type of RNA carries and transfers amino acids...Ch. 7 - What type of RNA carries the genetic information...Ch. 7 - Which of the following statements does not...Ch. 7 - Prob. 9SQCh. 7 - For the lac operon, match the following:Ch. 7 - Prob. 11SQCh. 7 - A frameshift mutation occurs following the: (a)...Ch. 7 - Prob. 13SQCh. 7 - Which of the following schemes for molecular...Ch. 7 - Suppose a point mutation occurred in the third...Ch. 7 - Prob. 16SQCh. 7 - (a) Why are bacteria useful in the study of...Ch. 7 - DNA damage in the form of dimers induced by UV...Ch. 7 - Prob. 19SQCh. 7 - Name and describe the effects of the following...
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- Explain what is meant by loss of function mutation. Name three different types of loss of function mutations and in each case explain how the mutation exerts a loss of function effect on a gene Explain the underlying cause of inborn errors of metabolism (a diagram can be used to illustrate your answer). Give an example of an inborn error of metabolism and explain how the underlying genetic defect leads to the symptoms seen in the diseasearrow_forwardDetermine the effect of the following mutations on the DNA sequence. In each case, the mutation is described after the sequence (REFER TO THE SUPPLEMENTAL DOCUMENT FOR GUIDANCE TO THIS QUESTION). Adenine nucleotide (A shown in red below) was inserted into the DNA sequence at the position indicated by the arrow). Write out the sequence of the mutated DNA and the protein made from it. What is the effect of this mutation on the protein? (For example, how will the mutation affect the length and sequence of the protein? What about the function of the protein?)arrow_forwardhttps://cancer.sanger.ac.uk/cosmic/gene/analysis?ln=TP73 using the above linke, Briefly describe the most common mutation found in this gene. Include details about the type of mutation, and the predicted effect. . where does the mutation occur, what bases are changed; does the mutation change the protein sequence, and if so what would the likely biologics consequences be?arrow_forward
- Which of the given disorder can be seen in an individual when the mutation includes substitution of a purine by pyrimidine? 1. Chronic myelogenous leukemia 2. Sickle cell anaemia 3. a thalassemia 4. B thalassemiaarrow_forwardA. Identify a substance or chemical in a certain product that could trigger a genetic disorder. B. Identify and describe the genetic disorder. C. Briefly explain the process on how the substance in letter A could trigger the genetic disorde.arrow_forwardChanges to the sequence of nucleotides in DNA, or changes to chromosomes, are calledarrow_forward
- Choose a syndrome or disorder caused by a mutation. Write the cause, type, and efffect of this mutation.arrow_forwardCompare the severity of DNA mutations that produce the following changes in mRNA codons:(a) GCU to GCC (b) ACU to AUUarrow_forwardDiscuss the possible effects of mutationsarrow_forward
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